2-Isopropyl 3-p-hydroxyphenylsulfonyl indolizine

Base Information

Chemical Name:2-Isopropyl 3-p-hydroxyphenylsulfonyl indolizine
CAS No.:121346-50-7
Molecular Formula:C17H17NO3S
Molecular Weight:315.393
Hs Code.:
DSSTox Substance ID:DTXSID001221829
Mol file:121346-50-7.mol

Synonyms:SCHEMBL7267038;PXEHWHZJTZXIHL-UHFFFAOYSA-N;DTXSID001221829;2-isopropyl 3-p-hydroxyphenylsulfonyl indolizine;4-[[2-(1-Methylethyl)-3-indolizinyl]sulfonyl]phenol;121346-50-7

Suppliers and Price of 2-Isopropyl 3-p-hydroxyphenylsulfonyl indolizine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Isopropyl 3-p-hydroxyphenylsulfonyl indolizine

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:315.09291458
Heavy Atom Count:22
Complexity:477

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)C1=C(N2C=CC=CC2=C1)S(=O)(=O)C3=CC=C(C=C3)O

Technology Process of 2-Isopropyl 3-p-hydroxyphenylsulfonyl indolizine

There total 5 articles about 2-Isopropyl 3-p-hydroxyphenylsulfonyl indolizine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.4%

: 121346-49-4
1-Carboxy-2-isopropyl-3-(4-hydroxybenzenesulphonyl)-indolizine

: 121346-50-7
2-Isopropyl-3-(4-hydroxybenzenesulphonyl)-indolizine

Guidance literature:: at 200 ℃; for 0.0333333h;
DOI:10.1021/jm00062a015

Reference yield:

: 127657-49-2
2-isopropyl 3-p-methoxyphenylsulfonyl indolizine

: 121346-50-7
2-Isopropyl-3-(4-hydroxybenzenesulphonyl)-indolizine

Guidance literature:: With hydrogenchloride; sodium hydrogencarbonate; ethanethiol; aluminium chloride; In dichloromethane;

Reference yield:

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 121346-50-7
2-Isopropyl-3-(4-hydroxybenzenesulphonyl)-indolizine

Guidance literature:: Multi-step reaction with 3 steps

1: 14 percent / AlCl₃ / 1,2-dichloro-ethane / 4 h / 0 - 20 °C

2: 44.6 percent / EtSH, AlCl₃ / CH₂Cl₂ / 0.75 h / Ambient temperature

3: 68.4 percent / 0.03 h / 200 °C

With aluminium trichloride; ethanethiol; In dichloromethane; 1,2-dichloro-ethane;
DOI:10.1021/jm00062a015