3-Hexyn-1-ol, 6-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-

Base Information

Chemical Name:3-Hexyn-1-ol, 6-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-
CAS No.:122069-55-0
Molecular Formula:C22H28O2Si
Molecular Weight:352.549
Hs Code.:
DSSTox Substance ID:DTXSID60448227
Wikidata:Q82267199

Synonyms:122069-55-0;3-Hexyn-1-ol, 6-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-;DTXSID60448227

Suppliers and Price of 3-Hexyn-1-ol, 6-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-Hexyn-1-ol, 6-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-

Chemical Property:

Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:7
Exact Mass:352.185856666
Heavy Atom Count:25
Complexity:424

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)[Si](C1=CC=CC=C1)(C2=CC=CC=C2)OCCC#CCCO

Technology Process of 3-Hexyn-1-ol, 6-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-

There total 2 articles about 3-Hexyn-1-ol, 6-[[(1,1-dimethylethyl)diphenylsilyl]oxy]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 75-21-8,99932-75-9
oxirane

: 88158-68-3
4-(tert-butyldiphenylsilyloxy)-1-butyne

: 122069-55-0
6-((tert-butyldiphenylsilyl)oxy)hex-3-yn-1-ol

Guidance literature:: With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; In tetrahydrofuran; diethyl ether; at -70 ℃;
DOI:10.1016/S0040-4039(00)61227-3

Reference yield:

: 58479-61-1
tert-butylchlorodiphenylsilane

: 122069-55-0
6-((tert-butyldiphenylsilyl)oxy)hex-3-yn-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / imidazole / dimethylformamide / 0.5 h / Ambient temperature

2: 1.) n-BuLi, hexamethylphosphoramide (HMPA), triphenylmethane / 1.) ether, THF, -40 deg C, 15 min, 2.) RT, 30 h

With 1H-imidazole; N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; triphenylmethane; In N,N-dimethyl-formamide;
DOI:10.1021/jo00276a025