1-(4-Cyanophenyl)-2-trifluoromethylimidazo[4,5-c]pyridine

Base Information

Chemical Name:1-(4-Cyanophenyl)-2-trifluoromethylimidazo[4,5-c]pyridine
CAS No.:122957-35-1
Molecular Formula:C14H7F3N4
Molecular Weight:288.232
Hs Code.:
DSSTox Substance ID:DTXSID601167625
Mol file:122957-35-1.mol

Synonyms:1-(4-cyanophenyl)-2-trifluoromethylimidazo[4,5-c]pyridine;SCHEMBL9726972;DTXSID601167625;122957-35-1;4-[2-(Trifluoromethyl)-1H-imidazo[4,5-c]pyridin-1-yl]benzonitrile

Suppliers and Price of 1-(4-Cyanophenyl)-2-trifluoromethylimidazo[4,5-c]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(4-Cyanophenyl)-2-trifluoromethylimidazo[4,5-c]pyridine

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:288.06228073
Heavy Atom Count:21
Complexity:422

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C#N)N2C3=C(C=NC=C3)N=C2C(F)(F)F

Technology Process of 1-(4-Cyanophenyl)-2-trifluoromethylimidazo[4,5-c]pyridine

There total 5 articles about 1-(4-Cyanophenyl)-2-trifluoromethylimidazo[4,5-c]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 75-90-1
2,2,2-Trifluoroacetaldehyde

: 122957-34-0
3-amino-4-[N-(4-cyanophenyl)amino]pyridine

: 122957-35-1
1-(4-cyanophenyl)-2-(trifluoromethyl)imidazo<4,5-c>pyridine

Guidance literature:: With sodium disulfite; In N,N-dimethyl acetamide; for 16h; Heating;
DOI:10.1021/jm00095a005

Reference yield:

: 13091-23-1
4-chloro-3-nitropyridine

: 122957-35-1
1-(4-cyanophenyl)-2-(trifluoromethyl)imidazo<4,5-c>pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 87 percent / ethanol / 18 h / 20 °C

2: 98 percent / H₂ / 10percent Pd/C / methanol; CH₂Cl₂ / 2 h / 20 °C / 1551.4 Torr

3: 59 percent / sodium metabisulfite / N,N-dimethyl-acetamide / 16 h / Heating

With sodium disulfite; hydrogen; palladium on activated charcoal; In methanol; ethanol; dichloromethane; N,N-dimethyl acetamide;
DOI:10.1021/jm00095a005

Reference yield:

: 122957-33-9
4-[N-(4-cyanophenyl)amino]-3-nitropyridine

: 122957-35-1
1-(4-cyanophenyl)-2-(trifluoromethyl)imidazo<4,5-c>pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / H₂ / 10percent Pd/C / methanol; CH₂Cl₂ / 2 h / 20 °C / 1551.4 Torr

2: 59 percent / sodium metabisulfite / N,N-dimethyl-acetamide / 16 h / Heating

With sodium disulfite; hydrogen; palladium on activated charcoal; In methanol; dichloromethane; N,N-dimethyl acetamide;
DOI:10.1021/jm00095a005