(3-(Benzyloxy)isoxazol-5-yl)methanol

Base Information

Chemical Name:(3-(Benzyloxy)isoxazol-5-yl)methanol
CAS No.:123320-44-5
Molecular Formula:C11H11NO3
Molecular Weight:205.213
Hs Code.:2934999090
DSSTox Substance ID:DTXSID20415894
Wikidata:Q82224959
Mol file:123320-44-5.mol

Synonyms:(3-(Benzyloxy)isoxazol-5-yl)methanol;123320-44-5;(3-phenylmethoxy-1,2-oxazol-5-yl)methanol;5-Isoxazolemethanol, 3-(phenylmethoxy)-;[3-(benzyloxy)-1,2-oxazol-5-yl]methanol;[3-(benzyloxy)isoxazol-5-yl]methanol;SCHEMBL322866;DTXSID20415894;AMY31212;YEA32044;MFCD23135734;AKOS016001729;CS-W021078;DS-2242;F2199-0080;InChI=1/C11H11NO3/c13-7-10-6-11(12-15-10)14-8-9-4-2-1-3-5-9/h1-6,13H,7-8H

Suppliers and Price of (3-(Benzyloxy)isoxazol-5-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(3-(Benzyloxy)isoxazol-5-yl)methanol >95%
1g
$ 864.00

Crysdot
(3-(Benzyloxy)isoxazol-5-yl)methanol 98%
1g
$ 347.00

Chemenu
(3-(benzyloxy)isoxazol-5-yl)methanol 95+%
1g
$ 327.00

American Custom Chemicals Corporation
(3-(BENZYLOXY)ISOXAZOL-5-YL)METHANOL 95.00%
5MG
$ 505.00

AK Scientific
(3-(Benzyloxy)isoxazol-5-yl)methanol
1g
$ 516.00

Total 15 raw suppliers

Chemical Property of (3-(Benzyloxy)isoxazol-5-yl)methanol

Chemical Property:

PSA：55.49000
LogP:1.74590
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:205.07389321
Heavy Atom Count:15
Complexity:183

Purity/Quality:

97% ^*data from raw suppliers

(3-(Benzyloxy)isoxazol-5-yl)methanol >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=NOC(=C2)CO
Uses (3-(Benzyloxy)isoxazol-5-yl)methanol is a key precursor to tetracycline antibiotics.

Technology Process of (3-(Benzyloxy)isoxazol-5-yl)methanol

There total 3 articles about (3-(Benzyloxy)isoxazol-5-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 205115-22-6
3-benzyloxyisoxazole-5-carboxylic acid methyl ester

: 123320-44-5
(3-(benzyloxy)isoxazol-5-yl)methanol

Guidance literature:: With methanol; sodium tetrahydroborate; at 15 ℃; for 3h;

Reference yield:

: 100-39-0
benzyl bromide

: 123320-44-5
(3-(benzyloxy)isoxazol-5-yl)methanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / acetone / 1 h / 70 °C

1.2: 5 h / 70 °C

2.1: sodium tetrahydroborate / methanol / 4 h / 0 °C

With sodium tetrahydroborate; potassium carbonate; In methanol; acetone;
DOI:10.1021/acs.jmedchem.5b00933

Reference yield:

: 100-39-0
benzyl bromide

: 123320-44-5
(3-(benzyloxy)isoxazol-5-yl)methanol

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / K₂CO₃ / acetone / 3 h / 70 °C

2: 87 percent / NaBH₄ / methanol / 22 h / 0 °C

With sodium tetrahydroborate; potassium carbonate; In methanol; acetone;
DOI:10.1002/(SICI)1099-0690(199803)1998:3<473::AID-EJOC473>3.0.CO;2-V