1,4-Dibromo-2,5-dibutoxybenzene

Base Information

• Chemical Name: 1,4-Dibromo-2,5-dibutoxybenzene
• CAS No.: 128915-84-4
• Molecular Formula: C14H20Br2O2
• Molecular Weight: 380.12
• DSSTox Substance ID: DTXSID90348680
• Nikkaji Number: J1.394.328A
• Wikidata: Q82123646
• Mol file: 128915-84-4.mol

Synonyms:1,4-dibromo-2,5-dibutoxybenzene;128915-84-4;1,4-DIBROMO-2,5-DI(BUTOXY)BENZENE;SCHEMBL2033249;DTXSID90348680;benzene, 1,4-dibromo-2,5-dibutoxy-

Chemical Property of 1,4-Dibromo-2,5-dibutoxybenzene

Chemical Property:

• PSA: 18.46000
• LogP: 5.56940
• XLogP3: 5.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 8
• Exact Mass: 379.98096
• Heavy Atom Count: 18
• Complexity: 192

Purity/Quality:

1,4-DIBROMO-2,5-DIBUTOXYBENZENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCOC1=CC(=C(C=C1Br)OCCCC)Br

Technology Process of 1,4-Dibromo-2,5-dibutoxybenzene

There total 6 articles about 1,4-Dibromo-2,5-dibutoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1,4-dibutoxybenzene (104-36-9) → 1,4-Dibromo-2,5-di-n-butoxybenzene (128915-84-4)

Guidance literature:

With bromine; acetic acid; at 20 ℃; for 10h;

DOI:10.1134/S0022476621060111

Reference yield: 96.0%

1-bromo-butane (109-65-9) + 2,5-dibromohydroquinone (14753-51-6) → 1,4-Dibromo-2,5-di-n-butoxybenzene (128915-84-4)

Guidance literature:

With potassium carbonate; In acetone; for 6h; Reflux;

DOI:10.1039/c6dt03086f

Reference yield:

hydroquinone (123-31-9,8027-02-9) → 1,4-Dibromo-2,5-di-n-butoxybenzene (128915-84-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 percent / NaOH / dimethylformamide / 18 h / 150 °C

2: 80 percent / Br₂ / CCl₄ / 70 h / Heating

With sodium hydroxide; bromine; In tetrachloromethane; N,N-dimethyl-formamide;

DOI:10.1039/b603603a

upstream raw materials:

1-bromo-butane

2,5-dibromohydroquinone

1,4-dibutoxybenzene

hydroquinone

Downstream raw materials:

1,4-dibutoxy-2,5-dicyanobenzene

1,4-dibutoxy-2,5-bis(thiophen-2-yl)benzene

1,4-Bis(3-hydroxy-3-methylbut-1-ynyl)-2,5-di-n-butoxybenzene

2,5-bis(butoxy)benzene-1,4-dialdehyde