1H-Benzimidazole, 2-[1-[4-(2-methylpropyl)phenyl]ethyl]-

Base Information

Chemical Name:1H-Benzimidazole, 2-[1-[4-(2-methylpropyl)phenyl]ethyl]-
CAS No.:129226-09-1
Molecular Formula:C19H22N2
Molecular Weight:278.397
Hs Code.:
DSSTox Substance ID:DTXSID00385501
ChEMBL ID:CHEMBL3355335
Mol file:129226-09-1.mol

Synonyms:129226-09-1;1H-Benzimidazole, 2-[1-[4-(2-methylpropyl)phenyl]ethyl]-;2-[1-[4-(2-methylpropyl)phenyl]ethyl]-1H-benzimidazole;2-{1-[4-(2-methylpropyl)phenyl]ethyl}-1H-benzimidazole;TimTec1_006039;Oprea1_048300;Oprea1_809410;CBDivE_008062;2-[1-(4-Isobutyl-phenyl)-ethyl]-1H-benzoimidazole;2-(1-(4-isobutylphenyl)ethyl)-1H-benzo[d]imidazole;SCHEMBL6757248;CHEMBL3355335;DTXSID00385501;HMS1551C11;STK067597;AKOS000275118;AKOS016040941;BB 0219462;EU-0045803;2-[1-(4-Isobutylphenyl)ethyl]-1H-benzimidazole;SR-01000499048;SR-01000499048-1;2-[1-(4-Isobutyl-phenyl)-ethyl]-1H-benzoimida zole;F1033-0048

Suppliers and Price of 1H-Benzimidazole, 2-[1-[4-(2-methylpropyl)phenyl]ethyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1H-Benzimidazole, 2-[1-[4-(2-methylpropyl)phenyl]ethyl]-

Chemical Property:

PSA：28.68000
LogP:4.91320
XLogP3:5.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:278.178298710
Heavy Atom Count:21
Complexity:320

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC1=CC=C(C=C1)C(C)C2=NC3=CC=CC=C3N2

Technology Process of 1H-Benzimidazole, 2-[1-[4-(2-methylpropyl)phenyl]ethyl]-

There total 4 articles about 1H-Benzimidazole, 2-[1-[4-(2-methylpropyl)phenyl]ethyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1382487-74-2
N-(2-aminophenyl)-2-(4-isobutylphenyl)propanamide

: 129226-09-1
2-<1-(4-isobutylphenyl)ethyl>-1H-benzimidazole

Guidance literature:: With acetic acid; for 4h; Reflux;
DOI:10.1016/j.bmc.2012.04.048

Reference yield: 90.0%

: 15687-27-1,58560-75-1
ibuprofen

: 39145-59-0
o-phenylenediamine hydrochloride

: 129226-09-1
2-<1-(4-isobutylphenyl)ethyl>-1H-benzimidazole

Guidance literature:: In ethylene glycol; for 3h; Heating;

Reference yield:

: 15687-27-1,58560-75-1
ibuprofen

: 129226-09-1
2-<1-(4-isobutylphenyl)ethyl>-1H-benzimidazole

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C

2: acetic acid / 4 h / Reflux

With dmap; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane;
DOI:10.1016/j.bmc.2012.04.048