Satranidazole

Base Information

Chemical Name:Satranidazole
CAS No.:56302-13-7
Molecular Formula:C8H11 N5 O5 S
Molecular Weight:289.272
Hs Code.:
European Community (EC) Number:611-377-1
UNII:4N7G8A6439
DSSTox Substance ID:DTXSID60204840
Nikkaji Number:J22.203H
Wikidata:Q27260233
NCI Thesaurus Code:C72155
ChEMBL ID:CHEMBL2105542
Mol file:56302-13-7.mol

Synonyms:1-methanesulfonyl-3-(1-methyl-5-nitroimidazol-2-yl)-2-imidazolidinone;CG-10213-Go;Go 10213;Go-10213;satranidazole

Suppliers and Price of Satranidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Satranidazole 96%
100mg
$ 1280.00

American Custom Chemicals Corporation
SATRANIDAZOLE 95.00%
5MG
$ 502.82

Total 45 raw suppliers

Chemical Property of Satranidazole

Chemical Property:

Vapor Pressure:2.48E-10mmHg at 25°C
Melting Point:185°C
Refractive Index:1.6460 (estimate)
Boiling Point:505.2°Cat760mmHg
PKA:2.49±0.25(Predicted)
Flash Point:259.3°C
PSA：129.71000
Density:1.77g/cm³
LogP:1.13680
XLogP3:-0.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:289.04808964
Heavy Atom Count:19
Complexity:497

Purity/Quality:

97% ^*data from raw suppliers

Satranidazole 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(=CN=C1N2CCN(C2=O)S(=O)(=O)C)[N+](=O)[O-]
Use Description **Satranidazole** is a pharmaceutical compound that serves important roles in the field of medicine. In the healthcare sector, it is primarily used as an antimicrobial agent and is especially valuable in the treatment of various infections, including bacterial and protozoal infections. Satranidazole is known for its efficacy against anaerobic bacteria and is commonly used in the management of infections of the gastrointestinal tract, genitourinary system, and various other body systems. Additionally, it has been utilized in the treatment of certain parasitic infections, such as amoebiasis and giardiasis. Its broad-spectrum antimicrobial properties make it a versatile drug in the field of medicine, contributing significantly to the management and eradication of a wide range of infectious diseases.

Technology Process of Satranidazole

There total 5 articles about Satranidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 41730-79-4
1-(methylsulphonyl)-2-oxo-2,3,4,5-tetrahydroimidazole

: 1615-53-8
1-methyl-2-methylsulphonyl-5-nitro-imidazole

: 56302-13-7
1 (1 methyl 5 nitroimidazol 2 yl) 3 (methylsulfonyl)imidazolidin 2 one

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; at 25 ℃; for 5h;

Reference yield:

: 85695-00-7
1-methylsulphonyl-3-(1-methyl-2-imidazolyl)-2-imidazolidinone

: 56302-13-7
1 (1 methyl 5 nitroimidazol 2 yl) 3 (methylsulfonyl)imidazolidin 2 one

Guidance literature:: With sulfuric acid; nitric acid; at 120 ℃; for 1.5h;

Reference yield:

: 1-(1-methyl-imidazolyl)-2-imidazolidinone hydrochloride

: 56302-13-7
1 (1 methyl 5 nitroimidazol 2 yl) 3 (methylsulfonyl)imidazolidin 2 one

Guidance literature:: Multi-step reaction with 2 steps

1: 0.1 g / NaH / dimethylformamide; dioxane / 1) 0-5 deg C, 1 h, 2) RT, 12 h

2: 15 mg / conc. H₂SO₄, HNO₃ (d 1.42) / 1.5 h / 120 °C

With sulfuric acid; nitric acid; sodium hydride; In 1,4-dioxane; N,N-dimethyl-formamide;