tert-Butyl [3-(2-chlorobenzoyl)thiophen-2-yl]carbamate

Base Information

Chemical Name:tert-Butyl [3-(2-chlorobenzoyl)thiophen-2-yl]carbamate
CAS No.:130534-59-7
Molecular Formula:C16H16ClNO3S
Molecular Weight:337.827
Hs Code.:
DSSTox Substance ID:DTXSID00564339
Wikidata:Q82449024

Synonyms:130534-59-7;tert-Butyl [3-(2-chlorobenzoyl)thiophen-2-yl]carbamate;DTXSID00564339

Suppliers and Price of tert-Butyl [3-(2-chlorobenzoyl)thiophen-2-yl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of tert-Butyl [3-(2-chlorobenzoyl)thiophen-2-yl]carbamate

Chemical Property:

XLogP3:5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:337.0539422
Heavy Atom Count:22
Complexity:424

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=C(C=CS1)C(=O)C2=CC=CC=C2Cl

Technology Process of tert-Butyl [3-(2-chlorobenzoyl)thiophen-2-yl]carbamate

There total 2 articles about tert-Butyl [3-(2-chlorobenzoyl)thiophen-2-yl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 40017-58-1
2-Amino-3-(o-chlorobenzoyl)-thiophene

: 24424-99-5
di-tert-butyl dicarbonate

: 130534-59-7
[3-(2-Chloro-benzoyl)-thiophen-2-yl]-carbamic acid tert-butyl ester

Guidance literature:: With sodium hydroxide; In tetrahydrofuran;
DOI:10.3987/COM-90-5442

Reference yield:

: 40018-25-5
2-Chlorobenzoyl acetonitrile

: 130534-59-7
[3-(2-Chloro-benzoyl)-thiophen-2-yl]-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 49 percent / Et₃N / dioxane

2: 63 percent / 10percent aq. NaOH / tetrahydrofuran

With sodium hydroxide; triethylamine; In tetrahydrofuran; 1,4-dioxane;
DOI:10.3987/COM-90-5442