1-(4-Chlorophenyl)-2-(methylamino)ethanol

Base Information

Chemical Name:1-(4-Chlorophenyl)-2-(methylamino)ethanol
CAS No.:131043-89-5
Molecular Formula:C9H12ClNO
Molecular Weight:185.653
Hs Code.:
DSSTox Substance ID:DTXSID50388628

Synonyms:1-(4-chlorophenyl)-2-(methylamino)ethanol;1-(4-chlorophenyl)-2-(methylamino)ethan-1-ol;131043-89-5;p-Chlorphenylaethanolmethylamin;SCHEMBL3704375;NIOSH/DN9505000;DTXSID50388628;PRHFCODVVHEZRP-UHFFFAOYSA-N;MFCD01732875;AKOS009145752;p-Chlorphenylaethanolmethylamin [German];LS-42779;NS-01677;DN95050000;EN300-1250352;p-Chloro-alpha-(methylaminomethyl)benzyl alcohol;Benzyl alcohol, p-chloro-alpha-(methylaminomethyl)-;F2148-0785;40587-06-2

Suppliers and Price of 1-(4-Chlorophenyl)-2-(methylamino)ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-(4-Chlorophenyl)-2-(methylamino)ethanol

Chemical Property:

XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:185.0607417
Heavy Atom Count:12
Complexity:124

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNCC(C1=CC=C(C=C1)Cl)O

Technology Process of 1-(4-Chlorophenyl)-2-(methylamino)ethanol

There total 2 articles about 1-(4-Chlorophenyl)-2-(methylamino)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 131101-44-5
(4R,5R)-5-(4-Chloro-phenyl)-4-(toluene-4-sulfonyl)-4,5-dihydro-oxazole

: 131043-89-5
(1R)-1-(4-chlorophenyl)-2-(2-methylamino)ethanol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; Ambient temperature;
DOI:10.1021/jo00311a007

Reference yield:

: 104-88-1
4-chlorobenzaldehyde

: 131043-89-5
(1R)-1-(4-chlorophenyl)-2-(2-methylamino)ethanol

Guidance literature:: Multi-step reaction with 2 steps

1: silver triflate-chiral ligand 1b / CH₂Cl₂ / 1 h / 25 °C

2: 89 percent / LiAlH₄ / tetrahydrofuran / Ambient temperature

With lithium aluminium tetrahydride; silver triflate-chiral ligand 1b; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo00311a007