(4R,5R)-5-(4-Chloro-phenyl)-4-(toluene-4-sulfonyl)-4,5-dihydro-oxazole

Base Information

Chemical Name:(4R,5R)-5-(4-Chloro-phenyl)-4-(toluene-4-sulfonyl)-4,5-dihydro-oxazole
CAS No.:131101-44-5
Molecular Formula:C₁₆H₁₄ClNO₃S
Molecular Weight:335.811
Hs Code.:

Synonyms:(4R,5R)-5-(4-Chloro-phenyl)-4-(toluene-4-sulfonyl)-4,5-dihydro-oxazole

Suppliers and Price of (4R,5R)-5-(4-Chloro-phenyl)-4-(toluene-4-sulfonyl)-4,5-dihydro-oxazole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4R,5R)-5-(4-Chloro-phenyl)-4-(toluene-4-sulfonyl)-4,5-dihydro-oxazole

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Technology Process of (4R,5R)-5-(4-Chloro-phenyl)-4-(toluene-4-sulfonyl)-4,5-dihydro-oxazole

There total 4 articles about (4R,5R)-5-(4-Chloro-phenyl)-4-(toluene-4-sulfonyl)-4,5-dihydro-oxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 38622-91-2,36635-61-7
[(p-methylphenyl)sulfonylmethyl]isonitrile

: 104-88-1
4-chlorobenzaldehyde

: 80225-02-1,131101-44-5
5-p-chlorophenyl-4-tosyl-2-oxazoline

Guidance literature:: With triethylamine; In methanol; at 20 ℃; optical yield given as %de; diastereoselective reaction;
DOI:10.2174/157017809788489855

Reference yield: 93.0%

: 10564-55-3
1-isocyanatomethanesulfonyl-4-methyl-benzene

: 104-88-1
4-chlorobenzaldehyde

: 80225-02-1,131101-44-5
5-p-chlorophenyl-4-tosyl-2-oxazoline

Guidance literature:: With DBN; In 1,2-dimethoxyethane; for 45h; Ambient temperature;

Reference yield:

: 38622-91-2,36635-61-7
[(p-methylphenyl)sulfonylmethyl]isonitrile

: 104-88-1
4-chlorobenzaldehyde

: 452086-44-1
(4S,5S)-5-(4-Chloro-phenyl)-4-(toluene-4-sulfonyl)-4,5-dihydro-oxazole

: 131101-44-5
(4R,5R)-5-(4-Chloro-phenyl)-4-(toluene-4-sulfonyl)-4,5-dihydro-oxazole

: 80225-02-1,131101-44-5
(4S,5R)-5-(4-Chloro-phenyl)-4-(toluene-4-sulfonyl)-4,5-dihydro-oxazole

Guidance literature:: silver triflate-chiral ligand 1b; In dichloromethane; at 25 ℃; for 1h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1021/jo00311a007