Methyl 2-[(2,6-dimethoxyphenyl)ethynyl]benzoate

Base Information

Chemical Name:Methyl 2-[(2,6-dimethoxyphenyl)ethynyl]benzoate
CAS No.:132338-41-1
Molecular Formula:C18H16O4
Molecular Weight:296.323
Hs Code.:
DSSTox Substance ID:DTXSID10563535
Wikidata:Q82447991

Synonyms:132338-41-1;Methyl 2-[(2,6-dimethoxyphenyl)ethynyl]benzoate;DTXSID10563535

Suppliers and Price of Methyl 2-[(2,6-dimethoxyphenyl)ethynyl]benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Methyl 2-[(2,6-dimethoxyphenyl)ethynyl]benzoate

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:296.10485899
Heavy Atom Count:22
Complexity:421

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C(=CC=C1)OC)C#CC2=CC=CC=C2C(=O)OC

Technology Process of Methyl 2-[(2,6-dimethoxyphenyl)ethynyl]benzoate

There total 2 articles about Methyl 2-[(2,6-dimethoxyphenyl)ethynyl]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 610-97-9
o-iodo-methyl-benzoic acid

: 126829-31-0
1-ethynyl-2,6-dimethoxybenzene

: 132338-41-1
methyl 2-<(2,6-dimethoxyphenyl)ethynyl>benzoate

Guidance literature:: copper(l) iodide; palladium;
DOI:10.1016/S0040-4039(00)97162-4

Reference yield:

: 132338-43-3
α-(2,6-dimethoxyphenyl)vinyl chloride

: 132338-41-1
methyl 2-<(2,6-dimethoxyphenyl)ethynyl>benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: 79.6 percent / LDA / hexane; tetrahydrofuran / 5 h / -78 deg C to r.t.

2: 56 percent / Pd⁽⁰⁾, CuI

With lithium diisopropyl amide; copper(l) iodide; palladium; In tetrahydrofuran; hexane;
DOI:10.1016/S0040-4039(00)97162-4