Toluene-4-sulfonic acid 1-methyl-piperidin-4-yl ester

Base Information

Chemical Name:Toluene-4-sulfonic acid 1-methyl-piperidin-4-yl ester
CAS No.:132710-79-3
Molecular Formula:C13H19NO3S
Molecular Weight:269.365
Hs Code.:
DSSTox Substance ID:DTXSID801208627
ChEMBL ID:CHEMBL1620706

Synonyms:132710-79-3;Toluene-4-sulfonic acid 1-methyl-piperidin-4-yl ester;1-methylpiperidin-4-yl 4-methylbenzenesulfonate;(1-methylpiperidin-4-yl) 4-methylbenzenesulfonate;NSC177947;1-methylpiperidin-4-yl 4-methylbenzene-1-sulfonate;1-Methyl-4-piperidinyl 4-methylbenzenesulfonate;SCHEMBL9705253;CHEMBL1620706;DTXSID801208627;AM91872;1-Methyl-4-piperidyl para-toluenesulphonate;1-methylpiperidin-4-yl4-methylbenzenesulfonate;(1-methyl-4-piperidyl) 4-methylbenzenesulfonate;EN300-5050588;Toluene-4-sulfonic acid 1-methylpiperidin-4-ylester;4-Piperidinol, 1-methyl-, 4-(4-methylbenzenesulfonate);Toluene-4-sulfonic acid 1-methyl-piperidin-4-yl ester hydrochloride

Suppliers and Price of Toluene-4-sulfonic acid 1-methyl-piperidin-4-yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Toluene-4-sulfonic acid 1-methyl-piperidin-4-yl ester

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:269.10856464
Heavy Atom Count:18
Complexity:347

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)OC2CCN(CC2)C

Technology Process of Toluene-4-sulfonic acid 1-methyl-piperidin-4-yl ester

There total 2 articles about Toluene-4-sulfonic acid 1-methyl-piperidin-4-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 106-52-5
N-methyl-4-hydroxypiperidine

: 98-59-9
p-toluenesulfonyl chloride

: 132710-79-3
1-methylpiperidin-4-yl-4-methylbenzenesulfonate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 2h;

Reference yield:

: 132710-79-3
1-methylpiperidin-4-yl-4-methylbenzenesulfonate

Guidance literature:

Reference yield: 54.0%

: 132710-79-3
1-methylpiperidin-4-yl-4-methylbenzenesulfonate

: 108756-88-3
(dicyclohexylphosphino)borane

: 181864-68-6
(C₆H₁₁)2P(BH₃)C₅H₉NCH₃

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; Ar-atmosphere; stirring (-78°C to room temp., 2 h), tosylate addn., -78°C (2 h), stirring (60°C, 6 h); evapn., NaHCO3 satd. soln. (H2O) addn., extg. (ether), evapn., chromy. (SiO2, MeOH); elem. anal.;
DOI:10.1021/om9603373