Methanone, (2-aminophenyl)[4-(phenylmethoxy)phenyl]-

Base Information

Chemical Name:Methanone, (2-aminophenyl)[4-(phenylmethoxy)phenyl]-
CAS No.:133776-45-1
Molecular Formula:C20H17NO2
Molecular Weight:303.36
Hs Code.:
DSSTox Substance ID:DTXSID80448986
Nikkaji Number:J397.273I
Wikidata:Q82268242

Synonyms:Methanone, (2-aminophenyl)[4-(phenylmethoxy)phenyl]-;133776-45-1;SCHEMBL7914507;2'-Amino-4-benzyloxybenzophenone;4'-benzyloxy-2-aminobenzophenone;DTXSID80448986;UIFFDAJFRQWWAB-UHFFFAOYSA-N

Suppliers and Price of Methanone, (2-aminophenyl)[4-(phenylmethoxy)phenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Methanone, (2-aminophenyl)[4-(phenylmethoxy)phenyl]-

Chemical Property:

XLogP3:4.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:303.125928785
Heavy Atom Count:23
Complexity:370

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=CC=C(C=C2)C(=O)C3=CC=CC=C3N

Technology Process of Methanone, (2-aminophenyl)[4-(phenylmethoxy)phenyl]-

There total 4 articles about Methanone, (2-aminophenyl)[4-(phenylmethoxy)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 6793-92-6
p-benzyloxyphenylbromide

: 133776-41-7
anthranilic acid N-methoxy-N-methylamide

: 133776-45-1
2-amino-4'-(phenylmethoxy)benzophenone

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.333333h;
DOI:10.1021/jo00011a066

Reference yield:

: 118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4
anthranilic acid

: 133776-45-1
2-amino-4'-(phenylmethoxy)benzophenone

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1,1'-carbonyldiimidazole / tetrahydrofuran / 2 h / 0 - 20 °C / Inert atmosphere

1.2: Inert atmosphere; Reflux

2.1: n-butyllithium / tetrahydrofuran / -78 °C / Inert atmosphere

With n-butyllithium; 1,1'-carbonyldiimidazole; In tetrahydrofuran;
DOI:10.1021/acs.joc.9b01418

Reference yield:

: 118-48-9
isatoic anhydride

: 133776-45-1
2-amino-4'-(phenylmethoxy)benzophenone

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / triethylamine / aq. ethanol / 1.5 h / Heating

2: 70 percent / n-BuLi / tetrahydrofuran; hexane / 0.33 h / -78 °C

With n-butyllithium; triethylamine; In tetrahydrofuran; ethanol; hexane;
DOI:10.1021/jo00011a066