Tris[4-(trifluoromethyl)phenyl]phosphane oxide

Base Information

• Chemical Name: Tris[4-(trifluoromethyl)phenyl]phosphane oxide
• CAS No.: 13406-27-4
• Molecular Formula: C21H12F9OP
• Molecular Weight: 482.285
• DSSTox Substance ID: DTXSID10502484
• Nikkaji Number: J402.388I
• Wikidata: Q82355575
• Mol file: 13406-27-4.mol

Synonyms:tris[4-(trifluoromethyl)phenyl]phosphane oxide;13406-27-4;C21H12F9OP;SCHEMBL6204533;DTXSID10502484;phosphorane, tris[4-(trifluoromethyl)phenyl]-, oxide;Oxotris[4-(trifluoromethyl)phenyl]-lambda~5~-phosphane

Chemical Property of Tris[4-(trifluoromethyl)phenyl]phosphane oxide

Chemical Property:

• XLogP3: 6.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 3
• Exact Mass: 482.04820546
• Heavy Atom Count: 32
• Complexity: 570

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1C(F)(F)F)P(=O)(C2=CC=C(C=C2)C(F)(F)F)C3=CC=C(C=C3)C(F)(F)F

Technology Process of Tris[4-(trifluoromethyl)phenyl]phosphane oxide

There total 10 articles about Tris[4-(trifluoromethyl)phenyl]phosphane oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

tris(para-trifluoromethyl)phenyl phosphine (13406-29-6) → tris(4-trifluoromethylphenyl)phosphine oxide (13406-27-4)

Guidance literature:

With dihydrogen peroxide; In dichloromethane; water; at 20 ℃; for 3h; Glovebox; Inert atmosphere;

DOI:10.1002/adsc.202100189

Reference yield: 78.0%

C17H7Cl4CuF6N3O2 + triphenylphosphine (603-35-0) → tris(4-trifluoromethylphenyl)phosphine oxide (13406-27-4) + nitrogen(II) oxide (10102-43-9) + C35H24Cl4CuF6N2P

Guidance literature:

In toluene; at 20 ℃; Kinetics; Glovebox; Sealed tube;

DOI:10.1021/acs.inorgchem.1c00625

Reference yield: 46.0%

C17H7Cl4CuF6N3O2 + tris(para-trifluoromethyl)phenyl phosphine (13406-29-6) → tris(4-trifluoromethylphenyl)phosphine oxide (13406-27-4) + nitrogen(II) oxide (10102-43-9) + C38H19Cl4CuF15N2P

Guidance literature:

In benzene-d6; for 1.5h;

DOI:10.1021/acs.inorgchem.1c00625

upstream raw materials:

tris(para-trifluoromethyl)phenyl phosphine

4-Dimethylamino-N--anilin

[(κ2-P,O-2-(bis(2-methoxyphenyl)phosphino)benzenesulfonato)PdMe(OP(p-CF3C6H4)3)]

p-trifluoromethylphenyl bromide

Downstream raw materials:

[(κ2-P,O-2-(bis(2-methoxyphenyl)phosphino)benzenesulfonato)PdMe(OP(p-CF3C6H4)3)]

bis(4-(trifluoromethyl)phenyl)phosphine oxide

(E)-[2-(1,2-diphenylethenyl)-4-(trifluoromethyl)phenyl]bis-[4-(trifluoromethyl)phenyl]phosphine oxide

tris(para-trifluoromethyl)phenyl phosphine

Refernces

• 1、 Joslin, Evan E.,Zaragoza, Jan Paulo T.,Baglia, Regina A.,Siegler, Maxime A.,Goldberg, David P.. "The Influence of Peripheral Substituent Modification on PV, MnIII, and MnV(O) Corrolazines: X-ray Crystallography, Electrochemical and Spectroscopic Properties, and HAT and OAT Reactivities". . p. 8646 - 8660. Retrieved 2016.
• 2、 Landais, Yannick,Laye, Claire,Lusseau, Jonathan,Robert, Frédéric. "The Trityl-Cation Mediated Phosphine Oxides Reduction". supporting information. p. 3035 - 3043. Retrieved 2021/05/10.
• 3、 Sadeghzadeh, Seyed Mohsen,Zhiani, Rahele. "Photooxidation of triarylphosphines under aerobic conditions in the presence of a gold(iii) complex on cellulose extracted from Carthamus tinctorius immobilized on nanofibrous phosphosilicate". . p. 1509 - 1516. Retrieved 2019/01/24.