4-(2-Hydroxyethyl)-3-nitrobenzoic acid

Base Information

Chemical Name:4-(2-Hydroxyethyl)-3-nitrobenzoic acid
CAS No.:134403-90-0
Molecular Formula:C9H9NO5
Molecular Weight:211.174
Hs Code.:
DSSTox Substance ID:DTXSID40568896
Wikidata:Q82455302
Mol file:134403-90-0.mol

Synonyms:4-(2-hydroxyethyl)-3-nitrobenzoic acid;134403-90-0;SCHEMBL8092214;DTXSID40568896

Suppliers and Price of 4-(2-Hydroxyethyl)-3-nitrobenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-(2-Hydroxyethyl)-3-nitrobenzoic acid

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:211.04807239
Heavy Atom Count:15
Complexity:249

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1C(=O)O)[N+](=O)[O-])CCO

Technology Process of 4-(2-Hydroxyethyl)-3-nitrobenzoic acid

There total 4 articles about 4-(2-Hydroxyethyl)-3-nitrobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 134403-89-7
4-(2-acetyloxyethyl)-3-nitrobenzonitrile

: 134403-90-0
4-(2-hydroxyethyl)-3-nitrobenzoic acid

Guidance literature:: With hydrogenchloride; In ethanol; for 16h; Heating;
DOI:10.1016/S0040-4020(01)92195-7

Reference yield:

: 69395-13-7
4-(2-hydroxyethyl)benzonitrile

: 134403-90-0
4-(2-hydroxyethyl)-3-nitrobenzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: acetic anhydride / 0.5 h / Ambient temperature

2: fuming nitric acid, conc. H₂SO₄ / 2 h / 0 °C

3: 77 percent / 12 N HCl / ethanol / 16 h / Heating

With hydrogenchloride; sulfuric acid; nitric acid; In ethanol; acetic anhydride;
DOI:10.1016/S0040-4020(01)92195-7

Reference yield:

: 4-cyanophenylethyl acetate

: 134403-90-0
4-(2-hydroxyethyl)-3-nitrobenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: fuming nitric acid, conc. H₂SO₄ / 2 h / 0 °C

2: 77 percent / 12 N HCl / ethanol / 16 h / Heating

With hydrogenchloride; sulfuric acid; nitric acid; In ethanol;
DOI:10.1016/S0040-4020(01)92195-7