1-(1,1-Dibromo-7-methoxyhept-1-en-5-yn-3-yl)-4-methoxybenzene

Base Information

Chemical Name:1-(1,1-Dibromo-7-methoxyhept-1-en-5-yn-3-yl)-4-methoxybenzene
CAS No.:136011-24-0
Molecular Formula:C15H16Br2O2
Molecular Weight:388.099
Hs Code.:
DSSTox Substance ID:DTXSID00569026
Mol file:136011-24-0.mol

Synonyms:136011-24-0;1-(1,1-Dibromo-7-methoxyhept-1-en-5-yn-3-yl)-4-methoxybenzene;DTXSID00569026

Suppliers and Price of 1-(1,1-Dibromo-7-methoxyhept-1-en-5-yn-3-yl)-4-methoxybenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-(1,1-Dibromo-7-methoxyhept-1-en-5-yn-3-yl)-4-methoxybenzene

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:387.94966
Heavy Atom Count:19
Complexity:342

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COCC#CCC(C=C(Br)Br)C1=CC=C(C=C1)OC

Technology Process of 1-(1,1-Dibromo-7-methoxyhept-1-en-5-yn-3-yl)-4-methoxybenzene

There total 4 articles about 1-(1,1-Dibromo-7-methoxyhept-1-en-5-yn-3-yl)-4-methoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 558-13-4
carbon tetrabromide

: 142396-16-5
6-methoxy-2-(4-methoxyphenyl)-4-hexynal

: 136011-24-0
1,1-dibromo-7-methoxy-3-(4-methoxyphenyl)-1-hepten-5-yne

Guidance literature:: With triphenylphosphine; In dichloromethane;
DOI:10.1016/S0040-4039(00)79766-8

Reference yield:

: 18857-03-9
4-methoxy-but-2-yn-1-ol

: 136011-24-0
1,1-dibromo-7-methoxy-3-(4-methoxyphenyl)-1-hepten-5-yne

Guidance literature:: Multi-step reaction with 4 steps

1: 76 percent / PBr₃, pyridine / diethyl ether / 1) -20 to 25 deg C, 2h, 2) 20 min, reflux

2: 1) LDA / 1) THF, HMPT, -80 deg C, 10-15 min, 2) THF, -80 to 0 deg C, 4h

3: 82 percent / DIBAL / diethyl ether; hexane / 1) -80 deg C, 3h, 2) -80 to -20 deg C

4: 86 percent / PPh₃ / CH₂Cl₂ / 0.58 h / 0 °C

With pyridine; phosphorus tribromide; diisobutylaluminium hydride; triphenylphosphine; lithium diisopropyl amide; In diethyl ether; hexane; dichloromethane;

Reference yield:

: 693-26-5
1-bromo-4-methoxy-but-2-yne

: 136011-24-0
1,1-dibromo-7-methoxy-3-(4-methoxyphenyl)-1-hepten-5-yne

Guidance literature:: Multi-step reaction with 3 steps

1: 1) LDA / 1) THF, HMPT, -80 deg C, 10-15 min, 2) THF, -80 to 0 deg C, 4h

2: 82 percent / DIBAL / diethyl ether; hexane / 1) -80 deg C, 3h, 2) -80 to -20 deg C

3: 86 percent / PPh₃ / CH₂Cl₂ / 0.58 h / 0 °C

With diisobutylaluminium hydride; triphenylphosphine; lithium diisopropyl amide; In diethyl ether; hexane; dichloromethane;