CYCLOPROPYL 2-PHENETHYL KETONE

Base Information

• Chemical Name: CYCLOPROPYL 2-PHENETHYL KETONE
• CAS No.: 136120-65-5
• Molecular Formula: C12H14O
• Molecular Weight: 174.243
• Mol file: 136120-65-5.mol

Synonyms:1-cyclopropyl-3-phenyl-propan-1-one;1-cyclopropyl-3-phenyl-1-propanone;1-Cyclopropyl-3-phenyl-propan-1-on;1-Propanone,1-cyclopropyl-3-phenyl;

Chemical Property of CYCLOPROPYL 2-PHENETHYL KETONE

Chemical Property:

• Vapor Pressure: 0.00603mmHg at 25°C
• Boiling Point: 272.6oC at 760 mmHg
• Flash Point: 111.6oC
• PSA: 17.07000
• Density: 1.077g/cm3
• LogP: 2.59830

Purity/Quality:

99.90% ^*data from raw suppliers

Cyclopropyl2-phenethylketone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CYCLOPROPYL 2-PHENETHYL KETONE

There total 21 articles about CYCLOPROPYL 2-PHENETHYL KETONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

Cyclopropyl methyl ketone (765-43-5) + benzyl alcohol (100-51-6,185532-71-2) → 1-cyclopropyl-3-phenyl-1-propanone (136120-65-5)

Guidance literature:

With bis(1,5-cyclooctadiene)diiridium(I) dichloride; triphenylphosphine; potassium hydroxide; at 100 ℃; for 4h; Inert atmosphere; Sealed tube;

DOI:10.1002/anie.201410391

Reference yield: 93.0%

1-cyclopropyl-3-phenylpropan-1-ol (52121-67-2) → 1-cyclopropyl-3-phenyl-1-propanone (136120-65-5)

Guidance literature:

With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; In dichloromethane; for 36h;

DOI:10.1021/jacs.5b11196

Reference yield: 86.0%

cyclopropylmagnesium bromide (23719-80-4) + phenylbutyric acid chloride (18496-54-3) → 1-cyclopropyl-3-phenyl-1-propanone (136120-65-5)

Guidance literature:

With copper(l) iodide; In tetrahydrofuran; at -78 - 20 ℃; for 18h;

DOI:10.1002/anie.201307950

upstream raw materials:

(E)-1-cyclopropyl-3-phenylpropen-1-one

Cyclopropyl methyl ketone

benzyl chloride

Chloroiodomethane

Downstream raw materials:

(±)1-cyclopropyl-2-methyl-3-phenylpropan-1-one

1-cyclopropyl-3-phenylpropan-1-ol