NOR-BETA-CIT

Base Information

Chemical Name:NOR-BETA-CIT
CAS No.:136794-87-1
Molecular Formula:C15H18 I N O2
Molecular Weight:371.218
Hs Code.:
Mol file:136794-87-1.mol

Synonyms:8-Azabicyclo[3.2.1]octane-2-carboxylicacid, 3-(4-iodophenyl)-, methyl ester, [1R-(exo,exo)]-; Nor-b-CIT; RTI 98

Suppliers and Price of NOR-BETA-CIT

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(-)-2β-Carbomethoxy-3β-(4-iodophenyl)nortropane
2.5mg
$ 150.00

American Custom Chemicals Corporation
(-)-2-BETA-CARBOMETHOXY-3-BETA-(4-IODOPHENYL)NORTROPANE 95.00%
5MG
$ 2057.00

American Custom Chemicals Corporation
(-)-2-BETA-CARBOMETHOXY-3-BETA-(4-IODOPHENYL)NORTROPANE 95.00%
0.5MG
$ 715.00

Total 11 raw suppliers

Chemical Property of NOR-BETA-CIT

Chemical Property:

Vapor Pressure:5.13E-07mmHg at 25°C
Boiling Point:412.6°C at 760 mmHg
Flash Point:203.3°C
PSA：38.33000
Density:1.528g/cm³
LogP:3.01710
Storage Temp.:−20°C
Solubility.:H2O: insoluble

Purity/Quality:

99% ^*data from raw suppliers

(-)-2β-Carbomethoxy-3β-(4-iodophenyl)nortropane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Uses An inhibitor of the serotonin (5-HT) transporter

Technology Process of NOR-BETA-CIT

There total 11 articles about NOR-BETA-CIT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 135416-43-2,133647-95-7
(1R,2S,3S,5S)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester

: 136794-87-1
(1R,2S,3S,5S)-3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester

Guidance literature:: (1R,2S,3S,5S)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester; With carbonochloridic acid 1-chloro-ethyl ester; In dichloromethane; Heating;

With methanol; Heating;
DOI:10.1016/j.bmcl.2004.12.014

Reference yield:

: 50372-80-0
WIN 35,065-2

: 136794-87-1
(1R,2S,3S,5S)-3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 59 percent / perchloric acid, mercuric oxide yellow, iodine / acetic acid / Ambient temperature

2: 54 percent / 1-chloroethyl chloroformate / 1,2-dichloro-ethane / 28 h / Heating

With perchloric acid; carbonochloridic acid 1-chloro-ethyl ester; iodine; mercury(II) oxide; In acetic acid; 1,2-dichloro-ethane;
DOI:10.1021/jm00034a021