1-Propanone, 3-(1H-imidazol-1-yl)-1-(2-naphthalenyl)-, monohydrochloride

Base Information

Chemical Name:1-Propanone, 3-(1H-imidazol-1-yl)-1-(2-naphthalenyl)-, monohydrochloride
CAS No.:75806-36-9
Molecular Formula:C₁₆H₁₄N₂O*ClH
Molecular Weight:286.761
Hs Code.:
DSSTox Substance ID:DTXSID40226722
ChEMBL ID:CHEMBL1743742

Synonyms:1-(2-(2-Naphthoyl)ethyl)imidazole hydrochloride;1-Propanone, 3-(1H-imidazol-1-yl)-1-(2-naphthalenyl)-, monohydrochloride;3-(1H-Imidazol-1-yl)-1-(2-naphthalenyl)-1-propanone monohydrochloride;75806-36-9;1-[2-(2-naphthoyl)ethyl]imidazole hydrochloride;CHEMBL1743742;SCHEMBL11252177;DTXSID40226722;JTTVRHHQNNUXGO-UHFFFAOYSA-N;LS-123074

Suppliers and Price of 1-Propanone, 3-(1H-imidazol-1-yl)-1-(2-naphthalenyl)-, monohydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-Propanone, 3-(1H-imidazol-1-yl)-1-(2-naphthalenyl)-, monohydrochloride

Chemical Property:

Vapor Pressure:2.95E-10mmHg at 25°C
Boiling Point:503.3°Cat760mmHg
Flash Point:258.2°C
Density:g/cm³
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:286.0872908
Heavy Atom Count:20
Complexity:318

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C=C(C=CC2=C1)C(=O)CCN3C=CN=C3.Cl

Technology Process of 1-Propanone, 3-(1H-imidazol-1-yl)-1-(2-naphthalenyl)-, monohydrochloride

There total 4 articles about 1-Propanone, 3-(1H-imidazol-1-yl)-1-(2-naphthalenyl)-, monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 288-32-4
1H-imidazole

: 2631-61-0
3-dimethylamino-1-(naphthalen-2-yl)propan-1-one hydrochloride

: 75806-36-9
1-<2-(2-naphthoyl)ethyl>imidazole hydrochloride

Guidance literature:: 1H-imidazole; 3-dimethylamino-1-(naphthalen-2-yl)propan-1-one hydrochloride; In water; for 1h; Reflux;

With hydrogenchloride; In diethyl ether; isopropyl alcohol; at 20 ℃;
DOI:10.1002/ardp.201200287

Reference yield:

: 93-08-3
methyl 2-naphthyl ketone

: 75806-36-9
1-<2-(2-naphthoyl)ethyl>imidazole hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride / isopropyl alcohol; water / Reflux

2.1: water / 1 h / Reflux

2.2: 20 °C

With hydrogenchloride; In water; isopropyl alcohol; 1.1: |Mannich Aminomethylation;
DOI:10.1002/ardp.201200287