4-Chloro-7-(trifluoromethyl)pyrrolo[1,2-A]quinoxaline

Base Information

Chemical Name:4-Chloro-7-(trifluoromethyl)pyrrolo[1,2-A]quinoxaline
CAS No.:136773-68-7
Molecular Formula:C₁₂H₆ClF₃N₂
Molecular Weight:270.641
Hs Code.:
DSSTox Substance ID:DTXSID00568776
Wikidata:Q82455129
Mol file:136773-68-7.mol

Synonyms:136773-68-7;4-CHLORO-7-(TRIFLUOROMETHYL)PYRROLO[1,2-A]QUINOXALINE;Pyrrolo[1,2-a]quinoxaline, 4-chloro-7-(trifluoromethyl)-;DTXSID00568776;MFCD33022356;BS-45379;E75005

Suppliers and Price of 4-Chloro-7-(trifluoromethyl)pyrrolo[1,2-A]quinoxaline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-Chloro-7-(trifluoromethyl)pyrrolo[1,2-A]quinoxaline

Chemical Property:

XLogP3:4.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:270.0171604
Heavy Atom Count:18
Complexity:323

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN2C3=C(C=C(C=C3)C(F)(F)F)N=C(C2=C1)Cl

Technology Process of 4-Chloro-7-(trifluoromethyl)pyrrolo[1,2-A]quinoxaline

There total 5 articles about 4-Chloro-7-(trifluoromethyl)pyrrolo[1,2-A]quinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 136773-66-5
7-(trifluoromethyl)pyrrolo<1,2-a>quinoxalin-4(5H)-one

: 136773-68-7
4-Chloro-7-trifluoromethyl-pyrrolo[1,2-a]quinoxaline

Guidance literature:: With trichlorophosphate; at 120 ℃; for 4h;
DOI:10.1080/00397919108021054

Reference yield:

: 136773-58-5
1H–1–(4–trifluoromethyl–2–nitrophenyl)pyrrole

: 136773-68-7
4-Chloro-7-trifluoromethyl-pyrrolo[1,2-a]quinoxaline

Guidance literature:: Multi-step reaction with 4 steps

2: 66 percent / 85percent KOH / 2-methyl-propan-2-ol / 1 h / 80 °C

3: 84 percent / K₂CO₃ / dimethylformamide / 1.5 h / 135 °C

4: 72 percent / POCl₃ / 4 h / 120 °C

With potassium hydroxide; potassium carbonate; trichlorophosphate; In N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1080/00397919108021054

Reference yield:

: 136773-59-6
1-<2-nitro-4-(trifluoromethyl)phenyl>-1H-pyrrole-2-carbonitrile

: 136773-68-7
4-Chloro-7-trifluoromethyl-pyrrolo[1,2-a]quinoxaline

Guidance literature:: Multi-step reaction with 3 steps

1: 66 percent / 85percent KOH / 2-methyl-propan-2-ol / 1 h / 80 °C

2: 84 percent / K₂CO₃ / dimethylformamide / 1.5 h / 135 °C

3: 72 percent / POCl₃ / 4 h / 120 °C

With potassium hydroxide; potassium carbonate; trichlorophosphate; In N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1080/00397919108021054