[1,1'-Bibicyclo[1.1.1]pentane]-3-carboxylic acid

Base Information

• Chemical Name: [1,1'-Bibicyclo[1.1.1]pentane]-3-carboxylic acid
• CAS No.: 137335-08-1
• Molecular Formula: C11H14O2
• Mol file: 137335-08-1.mol

Synonyms:

Chemical Property of [1,1'-Bibicyclo[1.1.1]pentane]-3-carboxylic acid

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [1,1'-Bibicyclo[1.1.1]pentane]-3-carboxylic acid

There total 1 articles about [1,1'-Bibicyclo[1.1.1]pentane]-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl ether (60-29-7,927820-24-4) + [1.1.1]propellane (35634-10-7) → bicyclo[1.1.1]pentane-1-carboxylic acid (22287-28-1) + 1-acetylbicyclo<1.1.1>pentane (137335-61-6) + 1-(1-acetoxyethyl)bicyclo<1.1.1>pentane (137335-60-5) + <2>staffane-3-carboxylic acid (137335-08-1)

Guidance literature:

With ruthenium(IV) oxide; Perbenzoic acid; Multistep reaction. Further byproducts given. Yields of byproduct given; 1.) irrad., 8 h, 2.) CCl₄, Chlorox;

DOI:10.1021/ja00028a029

Reference yield: 91.0%

<2>staffane-3-carboxylic acid (137335-08-1) → <2>staffane-3-carboxylic acid chloride (145143-26-6)

Guidance literature:

With thionyl chloride; for 6h; Heating;

DOI:10.1021/ja00052a070

upstream raw materials:

diethyl ether

[1.1.1]propellane

Downstream raw materials:

<2>staffane-3-carboxylic acid chloride