Sebacoyl chloride

Base Information

• Chemical Name: Sebacoyl chloride
• CAS No.: 111-19-3
• Molecular Formula: C10H16Cl2O2
• Molecular Weight: 239.142
• Hs Code.: 2917 19 80
• European Community (EC) Number: 203-843-4
• NSC Number: 56763
• UNII: 8JT2RJH7AU
• DSSTox Substance ID: DTXSID3059397
• Nikkaji Number: J193.590I
• Wikipedia: Sebacoyl chloride,Sebacoyl_chloride
• Wikidata: Q106902969
• Mol file: 111-19-3.mol

Synonyms:sebacoyl chloride

Chemical Property of Sebacoyl chloride

Chemical Property:

• Appearance/Colour: colourless to light yellow liquid with a pungent odour
• Vapor Pressure: 0.000787mmHg at 25°C
• Melting Point: -2.5 ºC
• Refractive Index: n20/D 1.468(lit.)
• Boiling Point: 306.1 °C at 760 mmHg
• Flash Point: 151.4 °C
• PSA: 34.14000
• Density: 1.135 g/cm³
• LogP: 3.63800
• Storage Temp.: 2-8°C
• Sensitive.: Moisture Sensitive
• Solubility.: Miscible with hydrocarbons and ethers.
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 9
• Exact Mass: 238.0527351
• Heavy Atom Count: 14
• Complexity: 161

Purity/Quality:

99% ^*data from raw suppliers

Sebacoyl chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T,C
• Statements: 22-24-34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Toxic Gases & Vapors -> Acid Halides
• Canonical SMILES: C(CCCCC(=O)Cl)CCCC(=O)Cl
• Uses: Sebacoyl Chloride can be used for cosmetic use that involves excellent activities of absorption and skin protection.

Technology Process of Sebacoyl chloride

There total 2 articles about Sebacoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,10-decanedioic acid (111-20-6,26776-29-4) → sebacoyl chloride (111-19-3)

Guidance literature:

With thionyl chloride; N,N-dimethyl-formamide; for 1.5h; Reflux;

Reference yield:

→ sebacoyl chloride (111-19-3)

Guidance literature:

Reference yield: 85.0%

sebacoyl chloride (111-19-3) → decanedial (45037-67-0)

Guidance literature:

With pentacoordinated hydrogenosilane 1;

DOI:10.1016/S0040-4039(00)80274-9

upstream raw materials:

1,10-decanedioic acid

Downstream raw materials:

methyl 10-chloro-10-oxodecanoate

1,10-bis-(4-bromo-phenyl)-decane-1,10-dione

1,10-bis(3,4-dimethoxyphenyl)-1,10-decanedione

10-oxohexadecanoic acid

Refernces

• 1、 Mansha, Muhammad,Ullah, Nisar,Kalgaonkar, Rajendra A.,Baqader, Nour. "Synthesis, Characterization, and Viscosification of Amidosulfobutaine and Zwitterionic Gemini Surfactants". . p. 697 - 706. Retrieved 2021.
• 2、 Spantulescu, Andreea,Luu, Thanh,Yuming, Zhao,McDonald, Robert,Tykwinski, Rik R.. "Synthesis and characterization of cyclic alkyl tetraynes". . p. 609 - 612. Retrieved 2008.
• 3、 Ishmuratov, G. Yu.,Sayakhov, R. R.,Talipov, R. F.,Vydrina, V. A.,Yakovleva, M. P.,Zileeva, Z. R.. "Synthesis of α,ω-Diketodiesters from Betulin". . p. 706 - 711. Retrieved 2021/07/31.
• 4、 -. "LIPID PRODRUGS OF PREGNANE NEUROSTEROIDS AND USES THEREOF". Paragraph 00293. . Retrieved 2020/02/23.