Dihydrocyclosporin H

Base Information

Chemical Name:Dihydrocyclosporin H
CAS No.:59865-15-5
Molecular Formula:C₆₂H₁₁₃N₁₁O₁₂
Molecular Weight:1204.65
Hs Code.:
European Community (EC) Number:806-474-2
Mol file:59865-15-5.mol

Synonyms:dihydrocyclosporin A

Suppliers and Price of Dihydrocyclosporin H

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Dihydrocyclosporin A
1mg
$ 362.00

TRC
DihydroCyclosporinA
5mg
$ 130.00

TRC
DihydroCyclosporinA
100mg
$ 1480.00

Biosynth Carbosynth
Dihydrocyclosporin A
25 mg
$ 700.00

Biosynth Carbosynth
Dihydrocyclosporin A
1 mg
$ 80.00

Biosynth Carbosynth
Dihydrocyclosporin A
2 mg
$ 120.00

Biosynth Carbosynth
Dihydrocyclosporin A
10 mg
$ 320.00

Biosynth Carbosynth
Dihydrocyclosporin A
5 mg
$ 180.00

AvaChem
Dihydrocyclosporin A
10mg
$ 149.00

AvaChem
Dihydrocyclosporin A
5mg
$ 99.00

Total 32 raw suppliers

Chemical Property of Dihydrocyclosporin H

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:120-125oC
Boiling Point:1285.277oC at 760 mmHg
PKA:13.33±0.70(Predicted)
Flash Point:731.109oC
PSA：278.80000
Density:1.012g/cm3
LogP:4.37350
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
XLogP3:8.2
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:16
Exact Mass:1203.85701808
Heavy Atom Count:85
Complexity:2280

Purity/Quality:

≥90% by HPLC ^*data from raw suppliers

Dihydrocyclosporin A ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCC(C)C(C1C(=O)NC(C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C)CC)O
Uses Dihydrocyclosporin A is a closely related co-metabolite of cyclosporin A. Dihydrocyclosporin A possesses no immunosuppressant activity and has found use as a control to determine the role of immunosuppression in the pharmacology of cyclosporin A, particularly in the treatment of parasitic infections. A Cyclosporin A (C988900) analog, an immunosuppressant.

Technology Process of Dihydrocyclosporin H

There total 6 articles about Dihydrocyclosporin H which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 59865-13-3,83602-39-5,122090-69-1,126374-36-5
cyclosporine A

: 59865-15-5,83602-88-4
C₆₂H₁₁₃N₁₁O₁₂

Guidance literature:: With hydrogen; palladium; In ethanol;
DOI:10.1016/S0040-4039(01)80693-6

Reference yield:

: 59865-13-3,83602-39-5,122090-69-1,126374-36-5
C₆₂H₁₁₁N₁₁O₁₂

: 59865-15-5,83602-88-4
C₆₂H₁₁₃N₁₁O₁₂

Guidance literature:: With hydrogen; palladium; In ethanol;
DOI:10.1016/S0040-4039(01)80693-6

Reference yield:

: 121584-52-9
C₆₂H₁₀₉N₁₁O₁₄

: 59865-15-5,83602-88-4
C₆₂H₁₁₃N₁₁O₁₂

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran / 2 h / 0 °C

2: CO₃^(2-) / methanol

3: H₂ / Pd / ethanol

With hydrogen; carbonate^(2-); palladium; In tetrahydrofuran; methanol; ethanol;
DOI:10.1016/S0040-4039(01)80693-6