4-Methyl-N'-[(4-nitrophenyl)methylidene]benzene-1-sulfonohydrazide

Base Information

• Chemical Name: 4-Methyl-N'-[(4-nitrophenyl)methylidene]benzene-1-sulfonohydrazide
• CAS No.: 1747-50-8
• Molecular Formula: C14H13 N3 O4 S
• Molecular Weight: 319.341
• DSSTox Substance ID: DTXSID10938547
• Mol file: 1747-50-8.mol

Synonyms:Maybridge1_000594;CBMicro_014943;DTXSID10938547;4-Methyl-N'-[(4-nitrophenyl)methylidene]benzene-1-sulfonohydrazide

Chemical Property of 4-Methyl-N'-[(4-nitrophenyl)methylidene]benzene-1-sulfonohydrazide

Chemical Property:

• Boiling Point: 503.9°Cat760mmHg
• Flash Point: 258.5°C
• Density: 1.35g/cm³
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 319.06267708
• Heavy Atom Count: 22
• Complexity: 493

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)NN=CC2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of 4-Methyl-N'-[(4-nitrophenyl)methylidene]benzene-1-sulfonohydrazide

There total 2 articles about 4-Methyl-N'-[(4-nitrophenyl)methylidene]benzene-1-sulfonohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

4-nitrobenzaldehdye (555-16-8) + toluene-4-sulfonic acid hydrazide (1576-35-8) → 4-methyl-N'-[(4-nitrophenyl)methylidene]benzene-1-sulfonohydrazide (1747-50-8)

Guidance literature:

In methanol; for 0.5h;

DOI:10.1021/ja034606+

Reference yield:

→ 4-methyl-N'-[(4-nitrophenyl)methylidene]benzene-1-sulfonohydrazide (1747-50-8)

Guidance literature:

Reference yield: 97.0%

4-methyl-N'-[(4-nitrophenyl)methylidene]benzene-1-sulfonohydrazide (1747-50-8) + methyl iodide (74-88-4) → N-methyl-N'-(4'-nitrobenzylidene)benzenesulfonohydrazide (1627-14-1)

Guidance literature:

With potassium carbonate; triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 36h; Inert atmosphere;

DOI:10.1016/j.tet.2013.05.131

upstream raw materials:

4-nitrobenzaldehdye

toluene-4-sulfonic acid hydrazide

Downstream raw materials:

potassium tosylate

2-nitro-benzenesulfonic acid ; potassium-compound

4-nitrobenzaldehdye

(4-nitrophenyl)diazomethane