9-Benzyl-1-ethyl-9H-beta-carbolin-4-ol

Base Information

Chemical Name:9-Benzyl-1-ethyl-9H-beta-carbolin-4-ol
CAS No.:138188-62-2
Molecular Formula:C20H18N2O
Molecular Weight:302.376
Hs Code.:
DSSTox Substance ID:DTXSID30568209
Wikidata:Q82454388
Mol file:138188-62-2.mol

Synonyms:138188-62-2;9-Benzyl-1-ethyl-9H-beta-carbolin-4-ol;DTXSID30568209

Suppliers and Price of 9-Benzyl-1-ethyl-9H-beta-carbolin-4-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 9-Benzyl-1-ethyl-9H-beta-carbolin-4-ol

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:302.141913202
Heavy Atom Count:23
Complexity:395

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=NC=C(C2=C1N(C3=CC=CC=C32)CC4=CC=CC=C4)O

Technology Process of 9-Benzyl-1-ethyl-9H-beta-carbolin-4-ol

There total 4 articles about 9-Benzyl-1-ethyl-9H-beta-carbolin-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 138188-61-1
9-benzyl-1-ethyl-4-oxo-1,2,3,4-tetrahydro-β-carboline

: 138188-62-2
9-benzyl-1-ethyl-4-hydroxy-β-carboline

Guidance literature:: palladium on activated charcoal; In decalin; at 140 ℃; for 8h;
DOI:10.1248/cpb.39.2189

Reference yield:

: 112402-18-3
1-(1-benzyl-1H-indol-2-yl)-1-propanone

: 138188-62-2
9-benzyl-1-ethyl-4-hydroxy-β-carboline

Guidance literature:: Multi-step reaction with 5 steps

1: HCONH₂, (NH₄)2SO₄ / 190 °C / 31920 - 68400.1 Torr

2: 70 percent / NaH

3: 80 percent / polyphosphoric acid (PPA)

4: conc. HCl

5: decalin / Pd/C

With hydrogenchloride; ammonium sulfate; PPA; Polyphosphoric acid (PPA); sodium hydride; formamide; decalin; palladium on activated charcoal;
DOI:10.3987/R-1987-04-0875

Reference yield:

: 138188-55-3
ethyl 2-methyl-3-oxo-3-(1-benzyl-1H-indol-2-yl)propionate

: 138188-62-2
9-benzyl-1-ethyl-4-hydroxy-β-carboline

Guidance literature:: Multi-step reaction with 6 steps

1: 30percent H₂SO₄, AcOH

2: HCONH₂, (NH₄)2SO₄ / 190 °C / 31920 - 68400.1 Torr

3: 70 percent / NaH

4: 80 percent / polyphosphoric acid (PPA)

5: conc. HCl

6: decalin / Pd/C

With hydrogenchloride; ammonium sulfate; PPA; Polyphosphoric acid (PPA); sulfuric acid; sodium hydride; formamide; acetic acid; decalin; palladium on activated charcoal;
DOI:10.3987/R-1987-04-0875