3-Aminopropyl(diethoxymethyl)phosphinic acid

Base Information

Chemical Name:3-Aminopropyl(diethoxymethyl)phosphinic acid
CAS No.:123690-79-9
Molecular Formula:C₈H₂₀NO₄P
Molecular Weight:225.225
Hs Code.:
UNII:87TI61875H
DSSTox Substance ID:DTXSID70154064
Nikkaji Number:J347.041E
Wikipedia:CGP-35348
Wikidata:Q5010979
ChEMBL ID:CHEMBL40157
Mol file:123690-79-9.mol

Synonyms:CGP 35348;CGP-35348;P-(3-aminopropyl)-P-diethoxymethylphosphinic acid

Suppliers and Price of 3-Aminopropyl(diethoxymethyl)phosphinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
CGP35348
10mg
$ 580.00

TRC
CGP35348
5mg
$ 315.00

Tocris
CGP35348
50
$ 818.00

Tocris
CGP35348
10
$ 203.00

Sigma-Aldrich
CGP 35348 hydrate ≥97% (NMR), solid
5mg
$ 172.00

Sigma-Aldrich
CGP 35348 hydrate ≥97% (NMR), solid
25mg
$ 587.00

Cayman Chemical
CGP 35348 ≥95%
50mg
$ 608.00

Cayman Chemical
CGP 35348 ≥95%
10mg
$ 135.00

ApexBio Technology
CGP35348
10mg
$ 187.00

American Custom Chemicals Corporation
CGP-35348 HYDRATE 95.00%
25MG
$ 1059.33

Total 11 raw suppliers

Chemical Property of 3-Aminopropyl(diethoxymethyl)phosphinic acid

Chemical Property:

Vapor Pressure:1.55E-07mmHg at 25°C
Boiling Point:400.5°Cat760mmHg
Flash Point:196°C
PSA：91.59000
Density:1.131g/cm³
LogP:1.66250
Storage Temp.:−20°C
Solubility.:H2O: >10 mg/mL
XLogP3:-3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:225.11299512
Heavy Atom Count:14
Complexity:182

Purity/Quality:

98%,99%, ^*data from raw suppliers

CGP35348 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(OCC)P(=O)(CCCN)O
Uses CGP 35348 hydrate has been used as a γ-aminobutyric acid-B (GABAB) receptor inhibitor:to study its effects on intrinsic optical signal (IOS) in rat hippocampusalone or in combination with sodium salicylate to study its effects on auditory responses in the rat′s dorsal cortex of ratto study its effects on hepatocellular carcinoma cells (HCC)

Technology Process of 3-Aminopropyl(diethoxymethyl)phosphinic acid

There total 5 articles about 3-Aminopropyl(diethoxymethyl)phosphinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 7440-44-0
pyrographite

: 103680-62-2
3-aminopropyl(diethoxymethyl)-phosphinic acid ethyl ester

: 123690-79-9
(3-aminopropyl)(diethoxymethyl)phosphinic acid

Guidance literature:: With lithium hydroxide monohydrate; In ethanol; water;

Reference yield:

: 123912-25-4
ethyl 2-cyanoethyl(diethoxymethyl)phosphinate

: 123690-79-9
(3-aminopropyl)(diethoxymethyl)phosphinic acid

Guidance literature:: Multi-step reaction with 2 steps

1: H₂, NH₃ / Raney nickel / ethanol / 4 h / 70 °C / 75006 Torr

2: aq. LiOH*H₂O / ethanol / Heating

With lithium hydroxide; ammonia; hydrogen; nickel; In ethanol;
DOI:10.1021/jm00017a016