1H-Pyrrole-3-carboxylic acid, 5-(4-chlorophenyl)-2-methyl-1-[4-[1-[3-(trifluoromethyl)phenyl]-1H-imidaz ol-4-yl]phenyl]-

Base Information

Chemical Name:1H-Pyrrole-3-carboxylic acid, 5-(4-chlorophenyl)-2-methyl-1-[4-[1-[3-(trifluoromethyl)phenyl]-1H-imidaz ol-4-yl]phenyl]-
CAS No.:138225-99-7
Molecular Formula:C28H19ClF3N3O2
Molecular Weight:521.926
Hs Code.:
Mol file:138225-99-7.mol

Synonyms:

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Chemical Property of 1H-Pyrrole-3-carboxylic acid, 5-(4-chlorophenyl)-2-methyl-1-[4-[1-[3-(trifluoromethyl)phenyl]-1H-imidaz ol-4-yl]phenyl]-

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Technology Process of 1H-Pyrrole-3-carboxylic acid, 5-(4-chlorophenyl)-2-methyl-1-[4-[1-[3-(trifluoromethyl)phenyl]-1H-imidaz ol-4-yl]phenyl]-

There total 4 articles about 1H-Pyrrole-3-carboxylic acid, 5-(4-chlorophenyl)-2-methyl-1-[4-[1-[3-(trifluoromethyl)phenyl]-1H-imidaz ol-4-yl]phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 138225-94-2
5-(4-Chloro-phenyl)-2-methyl-1-{4-[1-(3-trifluoromethyl-phenyl)-1H-imidazol-4-yl]-phenyl}-1H-pyrrole-3-carboxylic acid ethyl ester

: 138225-99-7
5-(4-Chloro-phenyl)-2-methyl-1-{4-[1-(3-trifluoromethyl-phenyl)-1H-imidazol-4-yl]-phenyl}-1H-pyrrole-3-carboxylic acid

Guidance literature:: With potassium hydroxide; In ethanol; water; for 1.5h; Heating;

Reference yield:

: 111787-82-7
2-[2-(4-chlorophenyl)-2-oxo-ethyl]-3-oxo-butyric acid ethyl ester

: 138225-99-7
5-(4-Chloro-phenyl)-2-methyl-1-{4-[1-(3-trifluoromethyl-phenyl)-1H-imidazol-4-yl]-phenyl}-1H-pyrrole-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / HBr / ethanol / 3 h / Heating

2: 80 percent / KOH / ethanol; H₂O / 1.5 h / Heating

With potassium hydroxide; hydrogen bromide; In ethanol; water;

Reference yield:

: 138225-80-6
4-[1-(3-Trifluoromethyl-phenyl)-1H-imidazol-4-yl]-phenylamine

: 138225-99-7
5-(4-Chloro-phenyl)-2-methyl-1-{4-[1-(3-trifluoromethyl-phenyl)-1H-imidazol-4-yl]-phenyl}-1H-pyrrole-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / HBr / ethanol / 3 h / Heating

2: 80 percent / KOH / ethanol; H₂O / 1.5 h / Heating

With potassium hydroxide; hydrogen bromide; In ethanol; water;