Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione,8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-6-(methylamino)-,[1aS-(1aa,8b,8aa,8ba)]- (9CI)

Base Information

Chemical Name:Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione,8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-6-(methylamino)-,[1aS-(1aa,8b,8aa,8ba)]- (9CI)
CAS No.:27066-44-0
Molecular Formula:C₁₆H₂₀N₄O₅
Molecular Weight:348.359
Hs Code.:

Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione,8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-6-(methylamino)-,[1aS-(1aa,8b,8aa,8ba)]- (9CI)

Synonyms:Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione,1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8aa-methoxy-5-methyl-6-(methylamino)-, carbamate (ester)(8CI); Carbamic acid, ester with1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methoxy-5-methyl-6-(methylamino)azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione(7CI); NSC 329086

Suppliers and Price of Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione,8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-6-(methylamino)-,[1aS-(1aa,8b,8aa,8ba)]- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione,8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-6-(methylamino)-,[1aS-(1aa,8b,8aa,8ba)]- (9CI)

Chemical Property:

Boiling Point:586.2°Cat760mmHg
Flash Point:308.3°C
Density:1.48g/cm³

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione,8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-6-(methylamino)-,[1aS-(1aa,8b,8aa,8ba)]- (9CI)

There total 3 articles about Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione,8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-6-(methylamino)-,[1aS-(1aa,8b,8aa,8ba)]- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

: 50-07-7
mitomycin C

: 74-88-4
methyl iodide

: 99831-88-6
C₁₆H₁₉N₃O₆

: 27066-44-0,4117-85-5
8-carbamoyloxymethyl-8a-methoxy-5-methyl-6-methylamino-1,1a,2,8,8a,8b-hexahydro-azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione

Guidance literature:: With sodium hydride; Yield given. Multistep reaction; 1.) DMF, room temp.; 2.) -20 deg C;
DOI:10.1016/S0040-4039(00)98688-X