8-O-methylretusin

Base Information

Chemical Name:8-O-methylretusin
CAS No.:37816-20-9
Molecular Formula:C17H14O5
Molecular Weight:298.295
Hs Code.:
DSSTox Substance ID:DTXSID90191259
Nikkaji Number:J595.800H
Wikidata:Q27187506
Metabolomics Workbench ID:22273
ChEMBL ID:CHEMBL477720
Mol file:37816-20-9.mol

Synonyms:8-O-methylretusin;Isoafrormosin;37816-20-9;Retusin 8-methyl ether;7-hydroxy-8-methoxy-3-(4-methoxyphenyl)chromen-4-one;SPBio_001888;8-methylretusin;Spectrum_000695;SpecPlus_000317;Spectrum2_001754;Spectrum3_000208;Spectrum4_001604;Spectrum5_000327;BSPBio_001795;KBioGR_001947;KBioSS_001175;DivK1c_006413;CHEMBL477720;SCHEMBL4293075;KBio1_001357;KBio2_001175;KBio2_003743;KBio2_006311;KBio3_001295;DTXSID90191259;CHEBI:108582;7-hydroxy-8,4'-dimethoxyisoflavone;CCG-38805;LMPK12050135;NCGC00179000-01;XM161627;7-HYDROXY-8,4;-DIMETHOXYISOFLAVONE;BRD-K09100418-001-02-6;Q27187506;7-hydroxy-8-methoxy-3-(4-methoxyphenyl)-4H-chromen-4-one;7-hydroxy-8-methoxy-3-(4-methoxyphenyl)-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 7-hydroxy-8-methoxy-3-(4-methoxyphenyl)-

Suppliers and Price of 8-O-methylretusin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 8-O-methylretusin

Chemical Property:

Vapor Pressure:2.51E-11mmHg at 25°C
Boiling Point:517.4°Cat760mmHg
Flash Point:194.2°C
PSA：68.90000
Density:1.321g/cm³
LogP:3.18280
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:298.08412354
Heavy Atom Count:22
Complexity:438

Purity/Quality:: 95%+ or 98%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3OC)O

Technology Process of 8-O-methylretusin

There total 3 articles about 8-O-methylretusin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 8-bromo-7-hydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one

: 124-41-4
sodium methylate

: 37816-20-9
7‐hydroxy‐8,4′‐dimethoxyisoflavone

Guidance literature:: With copper(I) bromide; In methanol; N,N-dimethyl-formamide; at 20 - 120 ℃; for 4.5h; Darkness;

Reference yield:

: 485-72-3
7-Hydroxy-3-(4-methoxy-phenyl)-chromen-4-on

: 37816-20-9
7‐hydroxy‐8,4′‐dimethoxyisoflavone

Guidance literature:: Multi-step reaction with 2 steps

1: N-Bromosuccinimide / N,N-dimethyl-formamide / 4 h / 0 °C

2: copper(I) bromide / N,N-dimethyl-formamide; methanol / 4.5 h / 20 - 120 °C / Darkness

With N-Bromosuccinimide; copper(I) bromide; In methanol; N,N-dimethyl-formamide;