2-(3-Chlorophenyl)-N-methyl-N-[2-(pyrrolidin-1-yl)ethyl]ethan-1-amine

Base Information

Chemical Name:2-(3-Chlorophenyl)-N-methyl-N-[2-(pyrrolidin-1-yl)ethyl]ethan-1-amine
CAS No.:138356-46-4
Molecular Formula:C₁₅H₂₃ClN₂
Molecular Weight:266.814
Hs Code.:
ChEMBL ID:CHEMBL142596
DSSTox Substance ID:DTXSID50568423
Nikkaji Number:J442.781E
Pharos Ligand ID:XYSQLC8Q36DQ

Synonyms:CHEMBL142596;138356-46-4;DTXSID50568423;BDBM50000074;2-(3-Chlorophenyl)-N-methyl-N-[2-(pyrrolidin-1-yl)ethyl]ethan-1-amine;[2-(3-Chloro-phenyl)-ethyl]-methyl-(2-pyrrolidin-1-yl-ethyl)-amine

Suppliers and Price of 2-(3-Chlorophenyl)-N-methyl-N-[2-(pyrrolidin-1-yl)ethyl]ethan-1-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-(3-Chlorophenyl)-N-methyl-N-[2-(pyrrolidin-1-yl)ethyl]ethan-1-amine

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:266.1549764
Heavy Atom Count:18
Complexity:229

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(CCC1=CC(=CC=C1)Cl)CCN2CCCC2

Technology Process of 2-(3-Chlorophenyl)-N-methyl-N-[2-(pyrrolidin-1-yl)ethyl]ethan-1-amine

There total 4 articles about 2-(3-Chlorophenyl)-N-methyl-N-[2-(pyrrolidin-1-yl)ethyl]ethan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 138356-74-8
2-(3-Chloro-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl-ethyl)-acetamide

: 138356-46-4
[2-(3-Chloro-phenyl)-ethyl]-methyl-(2-pyrrolidin-1-yl-ethyl)-amine

Guidance literature:: With aluminium hydride; In tetrahydrofuran; for 0.0833333h; Ambient temperature;
DOI:10.1021/jm00079a004

Reference yield:

: 32776-22-0
1-(2-methylaminoethyl)pyrrolidine

: 138356-46-4
[2-(3-Chloro-phenyl)-ethyl]-methyl-(2-pyrrolidin-1-yl-ethyl)-amine

Guidance literature:: Multi-step reaction with 2 steps

1: N,N'-dicyclohexylcarbodiimide (DCC) / CH₂Cl₂ / 0.5 h / Ambient temperature

2: AlH₃ / tetrahydrofuran / 0.08 h / Ambient temperature

With aluminium hydride; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm00079a004

Reference yield:

: 1878-65-5
3-chlorophenylacetic acid

: 138356-46-4
[2-(3-Chloro-phenyl)-ethyl]-methyl-(2-pyrrolidin-1-yl-ethyl)-amine

Guidance literature:: Multi-step reaction with 2 steps

1: N,N'-dicyclohexylcarbodiimide (DCC) / CH₂Cl₂ / 0.5 h / Ambient temperature

2: AlH₃ / tetrahydrofuran / 0.08 h / Ambient temperature

With aluminium hydride; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm00079a004