N-(2,5-Dichlorobenzyl)-N-methylamine

Base Information

• Chemical Name: N-(2,5-Dichlorobenzyl)-N-methylamine
• CAS No.: 90390-16-2
• Molecular Formula: C₈H₉Cl₂N
• Molecular Weight: 190.072
• Hs Code.: 2921499090
• DSSTox Substance ID: DTXSID50238139
• Wikidata: Q72465666
• ChEMBL ID: CHEMBL1178124
• Mol file: 90390-16-2.mol

Synonyms:N-(2,5-Dichlorobenzyl)-N-methylamine;90390-16-2;1-(2,5-dichlorophenyl)-n-methylmethanamine;Benzenemethanamine, 2,5-dichloro-N-methyl-;N-Methyl-2,5-dichlorobenzylamine;1-(2,5-dichlorophenyl)-N-methyl-methanamine;SCHEMBL3483104;CHEMBL1178124;DTXSID50238139;AKOS009345895;CS-0301497;FT-0658761;EN300-1237781;[(2,5-DICHLOROPHENYL)METHYL](METHYL)AMINE

Chemical Property of N-(2,5-Dichlorobenzyl)-N-methylamine

Chemical Property:

• Vapor Pressure: 0.0424mmHg at 25°C
• Refractive Index: 1.547
• Boiling Point: 238.4 °C at 760 mmHg
• Flash Point: 98 °C
• PSA: 12.03000
• Density: 1.226 g/cm³
• LogP: 3.10370
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 189.0112047
• Heavy Atom Count: 11
• Complexity: 119

Purity/Quality:

99% ^*data from raw suppliers

N-(2,5-Dichlorobenzyl)-N-methylamine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CNCC1=C(C=CC(=C1)Cl)Cl

Technology Process of N-(2,5-Dichlorobenzyl)-N-methylamine

There total 2 articles about N-(2,5-Dichlorobenzyl)-N-methylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2,5-dichloro-benzylidene)-methyl-amine → (2,5-Dichloro-benzyl)-methyl-amine (90390-16-2)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 2h; Heating;

DOI:10.1021/jm00375a005

Reference yield:

2,5-dichloro-benzaldehyde (6361-23-5) → (2,5-Dichloro-benzyl)-methyl-amine (90390-16-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1 h / 80 °C

2: LiAlH₄ / diethyl ether / 2 h / Heating

With lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1021/jm00375a005

upstream raw materials:

2,5-dichloro-benzaldehyde

Refernces