Technology Process of Glutathionylspermidine
There total 7 articles about Glutathionylspermidine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: isobutylchloroformate / dimethylformamide / 8 h / 4 °C
2: TFA / 0.75 h / Ambient temperature
3: aq. dithiothreitol
With
trifluoroacetic acid; diothiothreitol; isobutyl chloroformate;
In
N,N-dimethyl-formamide;
DOI:10.1039/c39860000593
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 70 percent / dimethylformamide / 10 h / Ambient temperature
2: 80 percent / dicyclohexylcarbodiimide / tetrahydrofuran / 8 h / 4 °C
3: dimethylformamide / 8 h / 4 °C
4: TFA / 0.75 h / Ambient temperature
5: aq. dithiothreitol
With
dicyclohexyl-carbodiimide; trifluoroacetic acid; diothiothreitol;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1039/c39860000593
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 80 percent / dicyclohexylcarbodiimide / tetrahydrofuran / 8 h / 4 °C
2: dimethylformamide / 8 h / 4 °C
3: TFA / 0.75 h / Ambient temperature
4: aq. dithiothreitol
With
dicyclohexyl-carbodiimide; trifluoroacetic acid; diothiothreitol;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1039/c39860000593
