Chemical Property of Myosmine
Chemical Property:
- Appearance/Colour:Light Yellow Powder
- Vapor Pressure:0.0468mmHg at 25°C
- Melting Point:42-44°C
- Boiling Point:82-83°C 0,5mm
- PKA:pK1:5.26 (25°C)
- Flash Point:101.8°C
- PSA：25.25000
- Density:1.12g/cm3
- LogP:1.10010
- Storage Temp.:2-8°C
- Solubility.:Methanol (Slightly), Water (Sparingly)
- XLogP3:0.6
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:2
- Rotatable Bond Count:1
- Exact Mass:146.084398327
- Heavy Atom Count:11
- Complexity:163
- Purity/Quality:
-
≥98% *data from raw suppliers
Myosmine *data from reagent suppliers
Safty Information:
- Pictogram(s):
R22:Harmful if swallowed.;
- Hazard Codes:Xn
- Statements:
22-36/37/38
- Safety Statements:
26-36
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C1CC(=NC1)C2=CN=CC=C2
-
Description
The alkaloids found in tobacco smoke may be separated into those which are
volatile in steam and those which are non-volatile. Myosmine occurs in the
former group and, although only present in small quantities, is the most fully
investigated of these bases. The alkaloid is normally obtained as an oily liquid
which may be crystallized. It is optically inactive and readily soluble in light
petroleum or Et20. It forms a hydrochloride as a microcrystalline powder which,
on sublimation yields colourless rods, m.p. ISS-8°C. The dihydrochloride, also a
microcrystalline powder, yields colourless needles on sublimation, m.p. 1S0-
17 Soc. The base also furnishes a dipicrate, m.p. 182-3°C (dec.) and a dipi_x0002_crolonate, m.p. 204°C (dec.). On dehydrogenation it gives 2-(3'-pyridyl)-pyrrole
(picrate, m.p. 200°C) identical with that obtained in a similar manner from nornicotine. According to Woodward and his colleagues, the alkaloid is one of
several products formed when nicotine is dehydrogenated over prepared quartz
at S70°C. It is readily hydrolyzed in H20 to yield 3-pyridyl-r-aminopropyl
ketone, forming a crystalline phenylhydrazone, m.p. 20l-2°C.
-
Uses
Myosmine is an alkaloid found in tobacco. Myosmine has been suspected to be a tobacco-independent carcinogenic source. mitogen Tobacco alkaloidReactant for:Nitrosation reactionsPeroxidation reaction with hydrogen peroxide
