Aids003506

Base Information

Chemical Name:Aids003506
CAS No.:134805-77-9
Molecular Formula:C44H58N8O6
Molecular Weight:794.9813
Hs Code.:

Synonyms:A76;1hvl;(2s,2's)-n,n'-[(2s,3r,4r,5s)-3,4-dihydroxy-1,6-diphenylhexane-2,5-diyl]bis(3-methyl-2-{[methyl(pyridin-2-ylmethyl)carbamoyl]amino}butanamide)(non-preferred name);

Suppliers and Price of Aids003506

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Aids003506

Chemical Property:

Boiling Point:1098.6°Cat760mmHg
Flash Point:618.2°C
PSA：203.08000
Density:1.209g/cm³
LogP:5.77500

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Aids003506

There total 20 articles about Aids003506 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: (2S,3S,4S,5S)-2,5-diamino-1,6-diphenylhexane-3,4-diol bistrifluoroacetate

: 134807-31-1
N-<carbonyl>valine p-nitrophenyl ester

: 134805-77-9
A 76928

Guidance literature:: With potassium carbonate; In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1021/jm701170f

Reference yield:

: 6306-52-1
L-valine methylester hydrochloride

: 134805-77-9
A 76889

Guidance literature:: Multi-step reaction with 5 steps

1: toluene / 6 h / 100 °C

2: CH₂Cl₂ / 2.5 h / Ambient temperature

3: 0.5M aq. LiOH / dioxane / 2 h

4: EDC / tetrahydrofuran; dimethylformamide / 4 h

5: tetrahydrofuran / 16 h / Ambient temperature

With lithium hydroxide; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In tetrahydrofuran; 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm00055a003

Reference yield:

: 6306-52-1
L-valine methylester hydrochloride

: 134805-77-9
A-77003

Guidance literature:: Multi-step reaction with 5 steps

1: toluene / 6 h / 100 °C

2: CH₂Cl₂ / 2.5 h / Ambient temperature

3: 0.5M aq. LiOH / dioxane / 2 h

4: EDC / tetrahydrofuran; dimethylformamide / 4 h

5: tetrahydrofuran / 16 h / Ambient temperature

With lithium hydroxide; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In tetrahydrofuran; 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm00055a003