4-Pyridazinecarbonitrile, 3-((2-(4-morpholinyl)ethyl)amino)-6-phenyl-, dihydrochloride

Base Information

Chemical Name:4-Pyridazinecarbonitrile, 3-((2-(4-morpholinyl)ethyl)amino)-6-phenyl-, dihydrochloride
CAS No.:94011-81-1
Molecular Formula:C₁₇H₁₉N₅O*2ClH
Molecular Weight:382.293
Hs Code.:
DSSTox Substance ID:DTXSID10240218

Synonyms:3-((2-(4-Morpholinyl)ethyl)amino)-6-phenyl-4-pyridazinecarbonitrile dihydrochloride;4-Pyridazinecarbonitrile, 3-((2-(4-morpholinyl)ethyl)amino)-6-phenyl-, dihydrochloride;94011-81-1;C17H19N5O.2ClH;SCHEMBL10830678;DTXSID10240218;BAMITKCNSQJVHG-UHFFFAOYSA-N;C17-H19-N5-O.2Cl-H;LS-129547;3-(2-Morpholinoethylamino)-4-cyano-6-phenylpyridazine dihydrochloride

Suppliers and Price of 4-Pyridazinecarbonitrile, 3-((2-(4-morpholinyl)ethyl)amino)-6-phenyl-, dihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-Pyridazinecarbonitrile, 3-((2-(4-morpholinyl)ethyl)amino)-6-phenyl-, dihydrochloride

Chemical Property:

Vapor Pressure:7.24E-14mmHg at 25°C
Boiling Point:589.3°Cat760mmHg
Flash Point:310.2°C
Density:g/cm³
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:381.1123157
Heavy Atom Count:25
Complexity:397

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1CCNC2=NN=C(C=C2C#N)C3=CC=CC=C3.Cl.Cl

Technology Process of 4-Pyridazinecarbonitrile, 3-((2-(4-morpholinyl)ethyl)amino)-6-phenyl-, dihydrochloride

There total 6 articles about 4-Pyridazinecarbonitrile, 3-((2-(4-morpholinyl)ethyl)amino)-6-phenyl-, dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 94011-50-4
ethyl 3-oxo-6-phenyl-2,3,4,5-tetrahydropyridazine-4-carboxylate

: 94011-81-1
3-(2-morpholinoethylamino)-4-cyano-6-phenylpyridazine dihydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 60 percent / bromine / acetic acid

2: 86 percent / conc. aq. NH₃ / 20 °C

3: 60 percent / POCl₃ / 3 h / 80 - 90 °C

With ammonium hydroxide; bromine; trichlorophosphate; In acetic acid;
DOI:10.1021/jm00123a004

Reference yield:

: 94011-49-1
diethyl phenacylmalonate

: 94011-81-1
3-(2-morpholinoethylamino)-4-cyano-6-phenylpyridazine dihydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1: 60 percent / hydrazine hydrate / ethanol / Ambient temperature

2: 60 percent / bromine / acetic acid

3: 86 percent / conc. aq. NH₃ / 20 °C

4: 60 percent / POCl₃ / 3 h / 80 - 90 °C

With ammonium hydroxide; bromine; hydrazine hydrate; trichlorophosphate; In ethanol; acetic acid;
DOI:10.1021/jm00123a004

Reference yield:

: 87769-56-0
2,3-dihydro-3-oxo-6-phenyl-4-pyridazinecarboxamide

: 94011-81-1
3-(2-morpholinoethylamino)-4-cyano-6-phenylpyridazine dihydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / POCl₃ / 3 h / 80 - 90 °C

With trichlorophosphate;
DOI:10.1021/jm00123a004