Pyrido[2,3-d]pyrimidin-4-amine, 7-(4-chlorophenyl)-5-phenyl-

Base Information

Chemical Name:Pyrido[2,3-d]pyrimidin-4-amine, 7-(4-chlorophenyl)-5-phenyl-
CAS No.:138744-57-7
Molecular Formula:C₁₉H₁₃ClN₄
Molecular Weight:332.792
Hs Code.:
DSSTox Substance ID:DTXSID90361213
Nikkaji Number:J504.765J
Wikidata:Q82143436

Synonyms:138744-57-7;Pyrido[2,3-d]pyrimidin-4-amine, 7-(4-chlorophenyl)-5-phenyl-;DTXSID90361213;5-Phenyl-7-(4-chlorophenyl)pyrido[2,3-d]pyrimidin-4-amine

Suppliers and Price of Pyrido[2,3-d]pyrimidin-4-amine, 7-(4-chlorophenyl)-5-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Pyrido[2,3-d]pyrimidin-4-amine, 7-(4-chlorophenyl)-5-phenyl-

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:332.0828741
Heavy Atom Count:24
Complexity:406

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC(=NC3=NC=NC(=C23)N)C4=CC=C(C=C4)Cl

Technology Process of Pyrido[2,3-d]pyrimidin-4-amine, 7-(4-chlorophenyl)-5-phenyl-

There total 2 articles about Pyrido[2,3-d]pyrimidin-4-amine, 7-(4-chlorophenyl)-5-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 75356-07-9
2-amino-6-(4-chlorophenyl)-4-phenylpyridine-3-carbonitrile

: 77287-34-4,77287-35-5,60100-09-6
formamide

: 138744-57-7
7-(4-chlorophenyl)-5-phenylpyrido[2,3-d]pyrimidin-4-amine

Guidance literature:: With pyridine; Reflux;
DOI:10.1002/jhet.2460

Reference yield:

: 956-02-5
4'-chlorochalcone

: 138744-57-7
7-(4-chlorophenyl)-5-phenylpyrido[2,3-d]pyrimidin-4-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 39 percent / ammonium acetate

2: formic acid / dimethylformamide / 10 h / Heating

With ammonium acetate; formic acid; In N,N-dimethyl-formamide;