(2E)-2-hydroxyimino-1-phenylpropan-1-ol

Base Information

• Chemical Name: (2E)-2-hydroxyimino-1-phenylpropan-1-ol
• CAS No.: 26226-58-4
• Molecular Formula: C9H11 N O2
• Molecular Weight: 165.192
• NSC Number: 50537
• DSSTox Substance ID: DTXSID80430083
• Mol file: 26226-58-4.mol

Synonyms:NSC50537;26226-58-4;SCHEMBL2639294;DTXSID80430083;NSC-50537

Chemical Property of (2E)-2-hydroxyimino-1-phenylpropan-1-ol

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 335.8°Cat760mmHg
• Flash Point: 207.6°C
• Density: 1.12g/cm³
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 165.078978594
• Heavy Atom Count: 12
• Complexity: 162

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=NO)C(C1=CC=CC=C1)O
• Isomeric SMILES: C/C(=N\O)/C(C1=CC=CC=C1)O

Technology Process of (2E)-2-hydroxyimino-1-phenylpropan-1-ol

There total 9 articles about (2E)-2-hydroxyimino-1-phenylpropan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-phenyl-1-<1-phenyl-5(1H)-tetrazolylthio>propan-2-one oxime (145614-27-3) → 1-Hydroxy-1-phenyl-2-propanone oxime (26226-58-4) + 1-Phenyl-1H-tetrazole-5-thiol (86-93-1)

Guidance literature:

With potassium hydroxide; In water; acetonitrile; at 22 ℃; Rate constant;

Reference yield:

→ 1-Hydroxy-1-phenyl-2-propanone oxime (26226-58-4)

Guidance literature:

With ethanol; palladium; racemat of mp: 116 degree; Hydrogenation;

DOI:10.1021/ja01357a029

Reference yield:

1-phenyl-1,2-propanedione 2-oxime (119-51-7) → 1-Hydroxy-1-phenyl-2-propanone oxime (26226-58-4)

Guidance literature:

With aluminium-chloride-diisopropylate; aluminum isopropoxide; isopropyl alcohol; Reagens 4:Benzol;

upstream raw materials:

(RS)-1-hydroxy-1-phenylpropan-2-one

1-phenyl-1,2-propanedione 2-oxime

1-phenyl-1-<1-phenyl-5(1H)-tetrazolylthio>propan-2-one oxime

trans-2-methyl-2-nitro-3-phenyloxirane

Downstream raw materials:

(RS)-1-hydroxy-1-phenylpropan-2-one

benzaldehyde

norephedrine

u-2-amino-1-phenylpropan-1-ol

Refernces

• 1、 Guthrie, J. Peter,Cossar, John. "The chlorination of propiophenone; determination of pKa value and the course of the reaction". . p. 2060 - 2069. Retrieved 2007/10/02.