Piperazine, 1-[5-fluoropentyl]-4-[(3,4-dichlorophenyl)acetyl]-

Base Information

Chemical Name:Piperazine, 1-[5-fluoropentyl]-4-[(3,4-dichlorophenyl)acetyl]-
CAS No.:141044-94-2
Molecular Formula:C17H23Cl2FN2O
Molecular Weight:361.28200
Hs Code.:
Mol file:141044-94-2.mol

Synonyms:2-(3,4-Dichloro-phenyl)-1-[4-(5-fluoro-pentyl)-piperazin-1-yl]-ethanone;

Suppliers and Price of Piperazine, 1-[5-fluoropentyl]-4-[(3,4-dichlorophenyl)acetyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of Piperazine, 1-[5-fluoropentyl]-4-[(3,4-dichlorophenyl)acetyl]-

Chemical Property:

Boiling Point:488.4±45.0 °C(Predicted)
PKA:7.12±0.10(Predicted)
PSA：23.55000
Density:1.216±0.06 g/cm3(Predicted)
LogP:3.69570

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Piperazine, 1-[5-fluoropentyl]-4-[(3,4-dichlorophenyl)acetyl]-

There total 3 articles about Piperazine, 1-[5-fluoropentyl]-4-[(3,4-dichlorophenyl)acetyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 407-66-9
5-<(methylsulfonyl)oxy>-1-pentyl fluoride

: 141044-84-0
1-<(3,4-dichlorophenyl)acetyl>piperazine

: 141044-94-2
1-(5-fluoro-1-pentyl)-4-<(3,4-dichlorophenyl)acetyl>piperazine

Guidance literature:: With sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 50 ℃;
DOI:10.1021/jm00090a012

Reference yield:

: 592-80-3
5-fluoro-1-pentanol

: 141044-94-2
1-(5-fluoro-1-pentyl)-4-<(3,4-dichlorophenyl)acetyl>piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: 66 percent / triethylamine / tetrahydrofuran / 0.17 h / 0 - 20 °C

2: 57 percent / NaHCO₃ / dimethylformamide / 50 °C

With sodium hydrogencarbonate; triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jm00090a012

Reference yield:

: 5807-30-7
3,4-dichlorophenyl acetic acid

: 141044-94-2
1-(5-fluoro-1-pentyl)-4-<(3,4-dichlorophenyl)acetyl>piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: DCC, triethylamine / CH₂Cl₂ / Ambient temperature

2: 57 percent / NaHCO₃ / dimethylformamide / 50 °C

With sodium hydrogencarbonate; triethylamine; dicyclohexyl-carbodiimide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm00090a012