5807-30-7

Basic information

• Product Name: 3,4-Dichlorophenylacetic acid
• Synonyms: TIMTEC-BB SBB003501;RARECHEM AL BO 0123;2-(3,4-DICHLOROPHENYL)ACETIC ACID;3,4-DICHLOROBENZENE ACETIC ACID;3,4-DICHLOROPHENYLACETIC ACID;LABOTEST-BB LT00455049;Benzeneacetic acid, 3,4-dichloro-;3,4-Dichlorophenylaceticacid,98%
• CAS NO: 5807-30-7
• Molecular Formula: C₈H₆Cl₂O₂
• Molecular Weight: 205.04
• EINECS: 227-368-7
• Product Categories: Aromatic Phenylacetic Acids and Derivatives;C8;Carbonyl Compounds;Carboxylic Acids;Building Blocks;Carbonyl Compounds;Carboxylic Acids;Chemical Synthesis;Organic Building Blocks
• Mol File: 5807-30-7.mol
• Article Data: 9

Chemical Properties

• Melting Point: 89-91 °C(lit.)
• Boiling Point: 294.45°C (rough estimate)
• Flash Point: 152.1 °C
• Appearance: white to light yellow crystalline powder
• Density: 1.3806 (rough estimate)
• Vapor Pressure: 7.9E-05mmHg at 25°C
• Refractive Index: 1.5490 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.99±0.10(Predicted)
• Water Solubility: Insoluble in water.
• BRN: 1953781
• CAS DataBase Reference: 3,4-Dichlorophenylacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Dichlorophenylacetic acid(5807-30-7)
• EPA Substance Registry System: 3,4-Dichlorophenylacetic acid(5807-30-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26-24/25
• WGK Germany: 3
• Hazardous Substances Data: 5807-30-7(Hazardous Substances Data)

Usage

Chemical Properties

white to light yellow crystalline powder

Uses

It is used in the parallel solid phase synthesis of tetra substituted diethylenetriamines via selective amide alkylation and exhaustive reduction of N-acylated dipeptides.

InChI:InChI=1/C8H6Cl2O2/c9-6-2-1-5(3-7(6)10)4-8(11)12/h1-3H,4H2,(H,11,12)/p-1

Upstream product

• 3218-49-3 3,4-dichloro-benzeneacetonitrile 
• 201230-82-2 carbon monoxide 
• 102-47-6 3,4-Dichlorophenylmethyl chloride 
• 18414-58-9 diphenylmethylsilanecarboxylic acid 
• 18880-04-1 3,4-dichlorobenzyl bromide 
• 3024-72-4 3,4-dichlorobenzoyl chloride 
• 51-44-5 3,4-dichlorbenzoic acid 
• 1805-32-9 3,4-dichlorobenzyl alcohol 
• 23722-52-3 2-diazo-1-(3,4-dichlorophenyl)ethan-1-one 

Downstream Products

• 6725-45-7 ethyl 3,4-dichlorophenylacetate 
• 150208-59-6 1-[1,4]Diazepan-1-yl-2-(3,4-dichloro-phenyl)-ethanone 
• 128103-38-8 1-<(3,4-dichlorophenyl)acetyl>-2-piperidinemethanol 
• 116763-50-9 N-[2-(3,4-dichlorophenyl)acetyl]-N-methyl-2-(1-pyrrolidinyl)ethylamine 
• 150208-58-5 1-<(3,4-dichlorophenyl)acetyl>-4-(1-propyl)piperazine 
• 138356-89-5 N-(2-Amino-ethyl)-2-(3,4-dichloro-phenyl)-acetamide 
• 79333-48-5 2-(S)-(3,4-dichloro-phenyl)-4-pentenoic acid 
• 856259-09-1 N-benzyl-N-[2-(4-benzyloxy-3-methoxy-phenyl)-ethyl]-2-(3,4-dichloro-phenyl)-acetamide 
• 856259-61-5 2-benzyl-7-benzyloxy-1-(3,4-dichloro-benzyl)-6-methoxy-1,2,3,4-tetrahydro-isoquinoline 
• 6831-55-6 2-(3,4-dichlorophenyl)acetyl chloride 
• 72191-59-4 α-bromo-(3,4-dichlorophenyl)acetic acid 
• 153905-75-0 2-(3,4-Dichloro-phenyl)-N-methyl-N-[2-(methyl-{2-[methyl-(2-pyrrolidin-1-yl-ethyl)-amino]-ethyl}-amino)-ethyl]-acetamide 
• 153905-88-5 2-(3,4-Dichloro-phenyl)-N-methyl-N-{3-[methyl-(3-pyrrolidin-1-yl-propyl)-amino]-propyl}-acetamide 
• 153905-66-9 2-(3,4-Dichloro-phenyl)-N-methyl-N-{2-[methyl-(2-pyrrolidin-1-yl-ethyl)-amino]-ethyl}-acetamide 

Relevant articles and documents

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Exceptionally simple catalytic system for the carbonylation of benzyl halides

A ligand-less catalytic system, Pd(OAc)2 immobilized in NBu4Hal melt is suggested for the synthesis of arylacetic acids by the carbonylation of benzyl bromides.

NOVEL POLYMORPHS OF AZABICYCLOHEXANE

The invention provides polymorphic crystalline forms of acid addition salts of (+)-1-(3, 4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane designated as polymorph form A, polymorph form B and polymorph form C, where polymorph form A is more thermodynamically stable than the other forms, methods for preparing and using such polymorph forms and pharmaceutical compositions containing such polymorph forms.