N-(2-Anilinopyridin-3-yl)-4-methylbenzene-1-sulfonamide

Base Information

Chemical Name:N-(2-Anilinopyridin-3-yl)-4-methylbenzene-1-sulfonamide
CAS No.:141430-60-6
Molecular Formula:C18H17N3O2S
Molecular Weight:339.418
Hs Code.:
ChEMBL ID:CHEMBL315466
DSSTox Substance ID:DTXSID60569582
Nikkaji Number:J497.058F
Wikidata:Q82456745

Synonyms:141430-60-6;CHEMBL315466;SCHEMBL8623823;DTXSID60569582;N-(2-Anilinopyridin-3-yl)-4-methylbenzene-1-sulfonamide

Suppliers and Price of N-(2-Anilinopyridin-3-yl)-4-methylbenzene-1-sulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of N-(2-Anilinopyridin-3-yl)-4-methylbenzene-1-sulfonamide

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:339.10414797
Heavy Atom Count:24
Complexity:477

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)NC2=C(N=CC=C2)NC3=CC=CC=C3

Technology Process of N-(2-Anilinopyridin-3-yl)-4-methylbenzene-1-sulfonamide

There total 6 articles about N-(2-Anilinopyridin-3-yl)-4-methylbenzene-1-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 34949-41-2
3-nitro-2-phenylaminopyridine

: 824-79-3
sodium 4-methylbenzenesulfinate

: 141430-60-6
4-methyl-N-(2-(phenylamino)pyridin-3-yl)benzenesulfonamide 5

Guidance literature:: With sodium hydrogensulfite; In water; dimethyl sulfoxide; at 60 ℃; for 24h; chemoselective reaction;
DOI:10.1016/j.tetlet.2018.10.032

Reference yield:

: 98-59-9
p-toluenesulfonyl chloride

: 41010-49-5
3-amino-2-phenylaminopyridine

: 141430-60-6
4-methyl-N-(2-(phenylamino)pyridin-3-yl)benzenesulfonamide 5

Guidance literature:: With pyridine; Ambient temperature;
DOI:10.1021/jm00091a018

Reference yield:

: 5470-18-8,34515-82-7
2-Chloro-3-nitropyridine

: 141430-60-6
4-methyl-N-(2-(phenylamino)pyridin-3-yl)benzenesulfonamide 5

Guidance literature:: Multi-step reaction with 3 steps

1: 100 °C

2: H₂

3: pyridine / Ambient temperature

With pyridine; hydrogen;
DOI:10.1021/jm00091a018