N-(2-Aminophenyl)-4-nitrobenzene-1-sulfonamide

Base Information

Chemical Name:N-(2-Aminophenyl)-4-nitrobenzene-1-sulfonamide
CAS No.:141469-52-5
Molecular Formula:C12H11N3O4S
Molecular Weight:293.303
Hs Code.:
DSSTox Substance ID:DTXSID00593604
Wikidata:Q82488109
Mol file:141469-52-5.mol

Synonyms:141469-52-5;Benzenesulfonamide, N-(2-aminophenyl)-4-nitro-;N-(2-Aminophenyl)-4-nitrobenzene-1-sulfonamide;n-(2-aminophenyl)-4-nitrobenzenesulfonamide;SCHEMBL6563189;DTXSID00593604;o-(p-nitrophenylsulfonylamino)aniline;DB-431763;EN300-1167891

Suppliers and Price of N-(2-Aminophenyl)-4-nitrobenzene-1-sulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N-(2-Aminophenyl)-4-nitrobenzene-1-sulfonamide

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:293.04702701
Heavy Atom Count:20
Complexity:435

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)N)NS(=O)(=O)C2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of N-(2-Aminophenyl)-4-nitrobenzene-1-sulfonamide

There total 3 articles about N-(2-Aminophenyl)-4-nitrobenzene-1-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 95-54-5
1,2-diamino-benzene

: 98-74-8
4-Nitrobenzenesulfonyl chloride

: 141469-52-5
o-(p-nitrophenylsulfonylamino)aniline

Guidance literature:: With triethylamine; In tetrahydrofuran; at 25 - 70 ℃; for 13h; Schlenk technique;
DOI:10.1002/aoc.2938

Reference yield:

: 88-74-4
2-nitro-aniline

: 141469-52-5
o-(p-nitrophenylsulfonylamino)aniline

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium tetrahydroborate / water / 0.03 h / 20 °C

2.1: triethylamine / tetrahydrofuran / 0.5 h / 20 °C

2.2: 20 °C

With sodium tetrahydroborate; triethylamine; In tetrahydrofuran; water;
DOI:10.1007/s00706-020-02679-2