Technology Process of Propanoic acid, 2-fluoro-2-methyl-3-(phenylmethoxy)-, methyl ester
There total 6 articles about Propanoic acid, 2-fluoro-2-methyl-3-(phenylmethoxy)-, methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: KOH, ethylene glycol / 150 °C
2: diethyl ether
With
potassium hydroxide; ethylene glycol;
In
diethyl ether;
DOI:10.3987/COM-91-S33
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 73 percent / m-CPBA, NaHCO3 / CH2Cl2 / 2 h / Ambient temperature
2: 69 percent / SiF4, (i-Pr)2NEt, H2O / diethyl ether / 2 h / 0 °C
3: Dess-Martin periodinane / CH2Cl2 / 2 h / Ambient temperature
4: aq. NaClO2, 2-methylbut-2-ene, phosphate buffer / 2-methyl-propan-2-ol / 2 h / Ambient temperature
5: tetrahydrofuran / 3 h / Ambient temperature
With
sodium chlorite; phosphate buffer; 2-methyl-but-2-ene; water; silicon tetrafluoride; sodium hydrogencarbonate; Dess-Martin periodane; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; diethyl ether; dichloromethane; tert-butyl alcohol;
DOI:10.1039/a702810e
- Guidance literature:
-
Multi-step reaction with 2 steps
1: aq. NaClO2, 2-methylbut-2-ene, phosphate buffer / 2-methyl-propan-2-ol / 2 h / Ambient temperature
2: tetrahydrofuran / 3 h / Ambient temperature
With
sodium chlorite; phosphate buffer; 2-methyl-but-2-ene;
In
tetrahydrofuran; tert-butyl alcohol;
DOI:10.1039/a702810e
