1,2,4-Triazolo(3,4-a)phthalazine, 6-(4-morpholinyl)-3-phenyl-

Base Information

Chemical Name:1,2,4-Triazolo(3,4-a)phthalazine, 6-(4-morpholinyl)-3-phenyl-
CAS No.:87539-85-3
Molecular Formula:C₁₉H₁₇N₅O
Molecular Weight:331.377
Hs Code.:
DSSTox Substance ID:DTXSID00236382
Wikidata:Q83118327
ChEMBL ID:CHEMBL13408

Synonyms:BRN 6437225;1,2,4-Triazolo(3,4-a)phthalazine, 6-(4-morpholinyl)-3-phenyl-;87539-85-3;6-(4-Morpholinyl)-3-phenyl-1,2,4-triazolo(3,4-a)phthalazine;CHEMBL13408;SCHEMBL10667034;C19H17N5O;DTXSID00236382;LS-156609

Suppliers and Price of 1,2,4-Triazolo(3,4-a)phthalazine, 6-(4-morpholinyl)-3-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,2,4-Triazolo(3,4-a)phthalazine, 6-(4-morpholinyl)-3-phenyl-

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.39g/cm³
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:331.14331018
Heavy Atom Count:25
Complexity:451

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COCCN1C2=NN3C(=NN=C3C4=CC=CC=C42)C5=CC=CC=C5

Technology Process of 1,2,4-Triazolo(3,4-a)phthalazine, 6-(4-morpholinyl)-3-phenyl-

There total 7 articles about 1,2,4-Triazolo(3,4-a)phthalazine, 6-(4-morpholinyl)-3-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51935-42-3,59275-72-8
1-chloro-4-hydrazinophthalazine

: 87539-85-3
4-(3-phenyl-1,2,4-triazolo[3,4-a]phthalazin-6-yl)morpholine

Guidance literature:: Multi-step reaction with 3 steps

1: 92 percent / 0.1N HCl / 0.17 h / 60 °C

2: 74 percent / Br₂, sodium acetate / acetic acid / 1 h / Ambient temperature

3: 70 percent / KI, HCl / ethanol / 8 h / 100 °C

With hydrogenchloride; bromine; sodium acetate; potassium iodide; In ethanol; acetic acid;
DOI:10.1021/jm00401a010

Reference yield:

: 100-52-7
benzaldehyde

: 87539-85-3
4-(3-phenyl-1,2,4-triazolo[3,4-a]phthalazin-6-yl)morpholine

Guidance literature:: Multi-step reaction with 3 steps

1: 92 percent / 0.1N HCl / 0.17 h / 60 °C

2: 74 percent / Br₂, sodium acetate / acetic acid / 1 h / Ambient temperature

3: 70 percent / KI, HCl / ethanol / 8 h / 100 °C

With hydrogenchloride; bromine; sodium acetate; potassium iodide; In ethanol; acetic acid;
DOI:10.1021/jm00401a010

Reference yield:

: 56813-52-6,67458-24-6
benzaldehyde (4-chloro-phthalazin-1-yl)-hydrazone

: 87539-85-3
4-(3-phenyl-1,2,4-triazolo[3,4-a]phthalazin-6-yl)morpholine

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / Br₂, sodium acetate / acetic acid / 1 h / Ambient temperature

2: 70 percent / KI, HCl / ethanol / 8 h / 100 °C

With hydrogenchloride; bromine; sodium acetate; potassium iodide; In ethanol; acetic acid;
DOI:10.1021/jm00401a010