7-Phenyl-2-heptanone

Base Information

• Chemical Name: 7-Phenyl-2-heptanone
• CAS No.: 14171-88-1
• Molecular Formula: C13H18O
• Molecular Weight: 190.285
• Hs Code.: 2914399090
• Mol file: 14171-88-1.mol

Synonyms:7-Phenyl-2-heptanone;2-Heptanone,7-phenyl;

Chemical Property of 7-Phenyl-2-heptanone

Chemical Property:

• PSA: 17.07000
• LogP: 3.37850

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-Phenyl-2-heptanone

There total 8 articles about 7-Phenyl-2-heptanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

4-Phenyl-1-butyne (16520-62-0) + 1-triphenylphosphoranylidene-2-propanone (1439-36-7) → 7-phenylheptan-2-one (14171-88-1)

Guidance literature:

With [2,2]bipyridinyl; formic acid; cyclopentadienylruthenium(II) trisacetonitrile hexafluorophosphate; water; In tetrahydrofuran; at 55 ℃; for 48h;

DOI:10.1038/nchem.1799

Reference yield: 69.0%

3-(iodomethyl)pentane (24346-54-1) + 4-penten-3-one (1629-58-9) → 7-phenylheptan-2-one (14171-88-1)

Guidance literature:

With tetrabutylammonium (cyano)trihydroborate; In methanol; for 6h; chemoselective reaction; Inert atmosphere; Irradiation;

DOI:10.1021/jo500464q

Reference yield: 47.0%

methyl vinyl ketone (78-94-4,25038-87-3) → 7-phenylheptan-2-one (14171-88-1)

Guidance literature:

With tri-n-butyl-tin hydride; tris(pyridine-2-carboxylato)manganese(III); In N,N-dimethyl-formamide; at 0 ℃; for 3h;

DOI:10.1246/cl.1993.1269

upstream raw materials:

2-acetyl-6-phenyl-hexanoic acid ethyl ester

1-Bromo-3-phenylpropane

methyl vinyl ketone

(E)-7-phenyl-3-hepten-2-one

Downstream raw materials:

7-azido-7-phenyl-2-heptanone

(E)-7-phenylhept-6-en-2-one

2-(1-methyl-6-phenylhexylidene)malononitrile

2-amino-4-methyl-5-(4-phenylbutyl)-thiophene-3-carbonitrile

Refernces

• 1、 Jiménez, M. Victoria,Fernández-Tornos, Javier,Modrego, F. Javier,Pérez-Torrente, Jesús J.,Oro, Luis A.. "Oxidation and β-Alkylation of Alcohols Catalysed by Iridium(I) Complexes with Functionalised N-Heterocyclic Carbene Ligands". supporting information. p. 17877 - 17889. Retrieved 2015/12/08.
• 2、 Kawamoto, Takuji,Uehara, Shohei,Hirao, Hidefumi,Fukuyama, Takahide,Matsubara, Hiroshi,Ryu, Ilhyong. "Borohydride-mediated radical addition reactions of organic iodides to electron-deficient alkenes". . p. 3999 - 4007. Retrieved 2014/05/20.