Methyl vinyl ketone

Base Information

• Chemical Name: Methyl vinyl ketone
• CAS No.: 78-94-4
• Molecular Formula: C4H6O
• Molecular Weight: 70.091
• Hs Code.: 29141990
• European Community (EC) Number: 201-160-6
• ICSC Number: 1495
• NSC Number: 4853
• UN Number: 1251
• UNII: AR7642I1MP
• DSSTox Substance ID: DTXSID3025671
• Nikkaji Number: J7H
• Wikipedia: Methyl_vinyl_ketone
• Wikidata: Q417525
• Metabolomics Workbench ID: 5424
• ChEMBL ID: CHEMBL1600824
• Mol file: 78-94-4.mol

Synonyms:1-Buten-3-one;2-Butenone;3-Oxo-1-butene;3-Oxobutene;NSC 4853;Vinylmethyl ketone;3-Buten-2-one;

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Methyl vinyl ketone

Chemical Property:

• Appearance/Colour: colourless liquid
• Vapor Pressure: 310 mm Hg ( 55 °C)
• Melting Point: -7 °C
• Refractive Index: n20/D 1.411(lit.)
• Boiling Point: 81.399 °C at 760 mmHg
• Flash Point: 20 °F
• PSA: 17.07000
• Density: 0.808 g/cm³
• LogP: 0.76140
• Storage Temp.: 2-8°C
• Solubility.: Chloroform (Sparingly), Methanol (Slightly)
• Water Solubility.: MISCIBLE
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 70.041864811
• Heavy Atom Count: 5
• Complexity: 54.7
• Transport DOT Label: Poison Inhalation Hazard Flammable Liquid Corrosive

Purity/Quality:

Safty Information:

• Pictogram(s): F; N; T+
• Hazard Codes: F,T+,N
• Statements: 11-26/27/28-34-43-50/53-26/28-68-40
• Safety Statements: 16-26-28-36/37/39-45-60-61-38

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Toxic Gases & Vapors -> Other Toxic Gases & Vapors
• Canonical SMILES: CC(=O)C=C
• Inhalation Risk: A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20 °C.
• Effects of Short Term Exposure: Lachrymation. The substance is corrosive to the eyes and skin. Corrosive on ingestion. The vapour is severely irritating to the eyes and respiratory tract. Inhalation may cause lung oedema. The substance may cause effects on the central nervous system.
• Effects of Long Term Exposure: Repeated or prolonged contact may cause skin sensitization.
• Description: Methyl vinyl ketone (MVK) is a stable, highly flammable, heatand light-sensitive, and colourless liquid. It is incompatible with strong bases, strong oxidising agents, and strong reducing agents and undergoes autopolymerisation. MVK is a reactive organic compound classified as an enone. It is a colourless to yellow, flammable, highly toxic liquid with a pungent odour. It is easily soluble in water, methanol, ethanol, and acetic acid. It can act as an alkylating agent. Its alkylating ability is both the source of its high toxicity and the feature that makes it a useful intermediate in organic synthesis. It polymerises spontaneously and is used in the manufacture of plastic polymers. It is also an intermediate in the synthesis of steroids and vitamin A.
• Uses: Alkylating agent; commercial starting material for plastics; as intermediate in the synthesis of steroids and vitamin A.

Technology Process of Methyl vinyl ketone

There total 265 articles about Methyl vinyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.7%

dimethylglyoxal (431-03-8) → dimethylketene (598-26-5) + propene (187737-37-7,13987-01-4,15220-87-8,9003-07-0,676-63-1,25085-53-4) + carbon dioxide (124-38-9,18923-20-1) + methyl vinyl ketone (78-94-4,25038-87-3) + prop-1-yne (74-99-7) + acetylene (74-86-2,25067-58-7)

Guidance literature:

With pyrographite; at -196 ℃; Mechanism;

DOI:10.1021/jo00180a047

Reference yield: 19.1%

isoprene (78-79-5,9003-31-0) → 3-methylfuran (930-27-8) + 2-methylpropenal (78-85-3,25120-30-3) + methyl vinyl ketone (78-94-4,25038-87-3) + 1-hydroxy-3-methylbut-3-en-2-one

Guidance literature:

With air; dihydrogen peroxide; for 0.5h; Further Variations:; Reagents; Product distribution; Kinetics; UV-irradiation;

DOI:10.1039/b002053m

Reference yield: 1.4%

3-diazo-2-butanone (14088-58-5) → dimethylketene (598-26-5) + propene (187737-37-7,13987-01-4,15220-87-8,9003-07-0,676-63-1,25085-53-4) + methyl vinyl ketone (78-94-4,25038-87-3)

Guidance literature:

at -196 ℃; Mechanism; Irradiation;

DOI:10.1021/jo00180a047

upstream raw materials:

oxirane

n-hexan-2-one

3-buten-1-yne

1-butylene

Downstream raw materials:

4-Ethylenimino-butan-2-on

4-(furan-2-yl)butan-2-one

4-[5-(3-oxobutyl)-2-furyl]-2-butanone

2-methyl-9H-carbazole

Refernces

• 1、 Knorr, Monika,Schmidt, Peer. "Reactivity of Ionic Liquids: Reductive Effect of [C4C1im]BF4 to Form Particles of Red Amorphous Selenium and Bi2Se3 from Oxide Precursors". . p. 125 - 140. Retrieved 2020/12/17.
• 2、 Adil, Syed Farooq,Assal, Mohamed E.,Shaik, Mohammed Rafi,Kuniyil, Mufsir,Hashmi, Azhar,Khan, Mujeeb,Khan, Aslam,Tahir, Muhammad Nawaz,Al-Warthan, Abdulrahman,Siddiqui, Mohammed Rafiq H.. "Efficient aerial oxidation of different types of alcohols using ZnO nanoparticle–MnCO3-graphene oxide composites". . . Retrieved 2020/06/08.