1H-Imidazole-1-propanamine, N-(3-chloro-2-nitrophenyl)-5-methyl-4-phenyl-N-(phenylmethyl)-

Base Information

Chemical Name:1H-Imidazole-1-propanamine, N-(3-chloro-2-nitrophenyl)-5-methyl-4-phenyl-N-(phenylmethyl)-
CAS No.:141816-08-2
Molecular Formula:C26H25ClN4O2
Molecular Weight:460.963
Hs Code.:

Synonyms:

Suppliers and Price of 1H-Imidazole-1-propanamine, N-(3-chloro-2-nitrophenyl)-5-methyl-4-phenyl-N-(phenylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 1H-Imidazole-1-propanamine, N-(3-chloro-2-nitrophenyl)-5-methyl-4-phenyl-N-(phenylmethyl)-

Chemical Property:

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Imidazole-1-propanamine, N-(3-chloro-2-nitrophenyl)-5-methyl-4-phenyl-N-(phenylmethyl)-

There total 10 articles about 1H-Imidazole-1-propanamine, N-(3-chloro-2-nitrophenyl)-5-methyl-4-phenyl-N-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 100-39-0
benzyl bromide

: 149156-06-9
3-chloro-2-nitro-N-<3-(5-methyl-4-phenyl-1H-imidazol-1-yl)propyl>aniline

: 141816-08-2
3-chloro-2-nitro-N-benzyl-N-<3-(5-methyl-4-phenyl-1H-imidazol-1-yl)propyl>aniline

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; for 1h; Ambient temperature;
DOI:10.1021/jm00063a013

Reference yield:

: 19088-99-4
3-chloro-2-nitrobenzoyl chloride

: 141816-08-2
3-chloro-2-nitro-N-benzyl-N-<3-(5-methyl-4-phenyl-1H-imidazol-1-yl)propyl>aniline

Guidance literature:: Multi-step reaction with 7 steps

1: NaN₃ / acetone; H₂O / 0.5 h / Ambient temperature

2: benzene / Heating

3: 5 N aq. NaOH / benzene / 1 h / Ambient temperature

4: 81 percent / 1 h / Heating

5: 50 percent / NaI, K₂CO₃ / dimethylformamide / 3 h / 60 °C

6: 100 percent / 2 N aq. HCl / dioxane / 0.5 h / Heating

7: 100 percent / NaH / dimethylformamide / 1 h / Ambient temperature

With hydrogenchloride; sodium hydroxide; sodium azide; sodium hydride; potassium carbonate; sodium iodide; In 1,4-dioxane; water; N,N-dimethyl-formamide; acetone; benzene;
DOI:10.1021/jm00063a013

Reference yield:

: 4771-47-5
3-chloro-2-nitro-benzoic acid

: 141816-08-2
3-chloro-2-nitro-N-benzyl-N-<3-(5-methyl-4-phenyl-1H-imidazol-1-yl)propyl>aniline

Guidance literature:: Multi-step reaction with 8 steps

1: SOCl₂ / 3 h / Heating

2: NaN₃ / acetone; H₂O / 0.5 h / Ambient temperature

3: benzene / Heating

4: 5 N aq. NaOH / benzene / 1 h / Ambient temperature

5: 81 percent / 1 h / Heating

6: 50 percent / NaI, K₂CO₃ / dimethylformamide / 3 h / 60 °C

7: 100 percent / 2 N aq. HCl / dioxane / 0.5 h / Heating

8: 100 percent / NaH / dimethylformamide / 1 h / Ambient temperature

With hydrogenchloride; sodium hydroxide; thionyl chloride; sodium azide; sodium hydride; potassium carbonate; sodium iodide; In 1,4-dioxane; water; N,N-dimethyl-formamide; acetone; benzene;
DOI:10.1021/jm00063a013