3-Chloroformyl-7-methoxycoumarin

Base Information

Chemical Name:3-Chloroformyl-7-methoxycoumarin
CAS No.:51867-62-0
Molecular Formula:C11H7 Cl O4
Molecular Weight:238.627
Hs Code.:2932209090
DSSTox Substance ID:DTXSID30199830
Nikkaji Number:J486.454I
Wikidata:Q83072834
Mol file:51867-62-0.mol

Synonyms:3-chloroformyl-7-methoxycoumarin;CFMOC

Suppliers and Price of 3-Chloroformyl-7-methoxycoumarin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of 3-Chloroformyl-7-methoxycoumarin

Chemical Property:

Vapor Pressure:7.5E-07mmHg at 25°C
Boiling Point:407.5°Cat760mmHg
Flash Point:182.9°C
PSA：56.51000
Density:1.444g/cm³
LogP:2.18060
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:238.0032864
Heavy Atom Count:16
Complexity:350

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C=C(C(=O)O2)C(=O)Cl

Technology Process of 3-Chloroformyl-7-methoxycoumarin

There total 5 articles about 3-Chloroformyl-7-methoxycoumarin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 20300-59-8
7-methoxycoumarin-3-carboxylic acid

: 51867-62-0
7-methoxy-2-oxo-2H-chromene-3-carbonyl chloride

Guidance literature:: With thionyl chloride; chloroform;

Reference yield:

: 673-22-3
2-Hydroxy-4-methoxybenzaldehyde

: 51867-62-0
7-methoxy-2-oxo-2H-chromene-3-carbonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: aniline / ethanol / 48 h / 20 °C

2: oxalyl chloride; pyridine / toluene

With pyridine; oxalyl dichloride; aniline; In ethanol; toluene; 1: Knoevenagel condensation;
DOI:10.1139/v02-006

Reference yield:

: 6093-72-7
7-methoxycoumarin-3-carboxylic acid ethyl ester

: 51867-62-0
7-methoxy-2-oxo-2H-chromene-3-carbonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 10percent KOH / ethanol

2: SOCl₂

With potassium hydroxide; thionyl chloride; In ethanol;