Carbamic acid, 1,3-pentadienyl-, 1,1-dimethylethyl ester, (E,E)- (9CI)

Base Information

• Chemical Name: Carbamic acid, 1,3-pentadienyl-, 1,1-dimethylethyl ester, (E,E)- (9CI)
• CAS No.: 141966-91-8
• Molecular Formula: C10H17NO2
• Molecular Weight: 183.24700
• Mol file: 141966-91-8.mol

Synonyms:1-(tert-butyloxycarbonylamino)-1,3-pentadiene;((1E,3E)-Penta-1,3-dienyl)-carbamic acid tert-butyl ester;1-(tert.-butyloxycarbonylamino)-1,3-pentadiene;

Chemical Property of Carbamic acid, 1,3-pentadienyl-, 1,1-dimethylethyl ester, (E,E)- (9CI)

Chemical Property:

• PSA: 38.33000
• LogP: 2.99180

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Carbamic acid, 1,3-pentadienyl-, 1,1-dimethylethyl ester, (E,E)- (9CI)

There total 1 articles about Carbamic acid, 1,3-pentadienyl-, 1,1-dimethylethyl ester, (E,E)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sorbic azide (65899-52-7) + tert-butyl alcohol (75-65-0) → tert-butyl ((1E,3E)-penta-1,3-dien-1-yl)carbamate (141966-91-8,131784-71-9)

Guidance literature:

With 2,6-di-tert-butyl-4-methyl-phenol; In toluene; for 3h; Heating;

DOI:10.1021/ja060282o

Reference yield: 79.0%

tert-butyl ((1E,3E)-penta-1,3-dien-1-yl)carbamate (141966-91-8,131784-71-9) + (5-methoxy-1H-indol-3-yl)(phenyl)methanol (1263063-05-3) → tert-butyl ((6S,9R,10S)-2-methoxy-9-methyl-10-phenyl-5,6,9,10-tetrahydrocyclohepta[b]indol-6-yl)carbamate

Guidance literature:

With (S)-3,3'-bis(2,4,6-tri-iso-propylphenyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; In toluene; at 0 - 20 ℃; stereoselective reaction; Molecular sieve;

DOI:10.1002/anie.201807069

Reference yield: 46.0%

tert-butyl ((1E,3E)-penta-1,3-dien-1-yl)carbamate (141966-91-8,131784-71-9) + (2-methyl-1H-indol-3-yl)(phenyl)methanol (438479-05-1) → tert-butyl ((1S,2R,5R,6R)-2',5-dimethyl-6-phenyl-spiro[cyclohexane-1,3'-indol]-3-en-2-yl)carbamate

Guidance literature:

With C₄₈H₃₇O₄P; In 1,2-dichloro-ethane; at -20 - 60 ℃; for 27h; enantioselective reaction; Molecular sieve; Inert atmosphere;

DOI:10.1021/jacs.1c04648

upstream raw materials:

sorbic azide

tert-butyl alcohol