n-[2-(1,3-Benzodioxol-5-yl)ethyl]-2-(2-nitrophenyl)acetamide

Base Information

Chemical Name:n-[2-(1,3-Benzodioxol-5-yl)ethyl]-2-(2-nitrophenyl)acetamide
CAS No.:73903-39-6
Molecular Formula:C17H16N2O5
Molecular Weight:328.3193
Hs Code.:
NSC Number:114756
DSSTox Substance ID:DTXSID90297220
Wikidata:Q82038225

Synonyms:n-[2-(1,3-benzodioxol-5-yl)ethyl]-2-(2-nitrophenyl)acetamide;73903-39-6;NSC114756;DTXSID90297220;NSC-114756

Suppliers and Price of n-[2-(1,3-Benzodioxol-5-yl)ethyl]-2-(2-nitrophenyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of n-[2-(1,3-Benzodioxol-5-yl)ethyl]-2-(2-nitrophenyl)acetamide

Chemical Property:

Vapor Pressure:2.2E-13mmHg at 25°C
Boiling Point:578.6°Cat760mmHg
Flash Point:303.7°C
Density:1.34g/cm³
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:328.10592162
Heavy Atom Count:24
Complexity:453

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1OC2=C(O1)C=C(C=C2)CCNC(=O)CC3=CC=CC=C3[N+](=O)[O-]

Technology Process of n-[2-(1,3-Benzodioxol-5-yl)ethyl]-2-(2-nitrophenyl)acetamide

There total 5 articles about n-[2-(1,3-Benzodioxol-5-yl)ethyl]-2-(2-nitrophenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 3740-52-1
2-(2-nitrophenyl)acetic acid

: 1484-85-1
3,4-methylenedioxyphenylethylamine

: 73903-39-6
N-(2-(benzo[d][1,3]dioxol-5-yl)ethyl)-2-(2-nitrophenyl)acetamide

Guidance literature:: With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In tetrahydrofuran; at 20 ℃;
DOI:10.1002/cmdc.201300332

Reference yield: 85.0%

: 22751-23-1
(2-nitrophenyl)acetyl chloride

: 1484-85-1
3,4-methylenedioxyphenylethylamine

: 73903-39-6
N-(2-(benzo[d][1,3]dioxol-5-yl)ethyl)-2-(2-nitrophenyl)acetamide

Guidance literature:: 3,4-methylenedioxyphenylethylamine; With potassium carbonate; In dichloromethane; water; at 0 - 5 ℃;

(2-nitrophenyl)acetyl chloride; In dichloromethane; water; at 0 - 5 ℃; for 2h;
DOI:10.1039/c8ra05338c

Reference yield:

: 120-57-0,30024-74-9
piperonal

: 73903-39-6
N-(2-(benzo[d][1,3]dioxol-5-yl)ethyl)-2-(2-nitrophenyl)acetamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: ethylenediamine / 5 h / Reflux

2.1: lithium aluminium tetrahydride / tetrahydrofuran / Reflux

3.1: potassium carbonate / dichloromethane; water / 0 - 5 °C

3.2: 2 h / 0 - 5 °C

With lithium aluminium tetrahydride; potassium carbonate; ethylenediamine; In tetrahydrofuran; dichloromethane; water;
DOI:10.1039/c8ra05338c