2-Nitrophenylacetic acid

Base Information

Chemical Name:2-Nitrophenylacetic acid
CAS No.:3740-52-1
Molecular Formula:C8H7NO4
Molecular Weight:181.148
Hs Code.:29163900
European Community (EC) Number:223-128-0
NSC Number:16624
UNII:05TN0SUY38
DSSTox Substance ID:DTXSID0063157
Nikkaji Number:J714.505E,J27.572G
Wikidata:Q27236144
Mol file:3740-52-1.mol

Synonyms:(2-nitrophenyl)acetic acid;2-nitrophenylacetic acid;o-nitrophenylacetic acid

Suppliers and Price of 2-Nitrophenylacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2-Nitrophenylacetic acid
250g
$ 322.00

TRC
2-Nitrophenylacetic acid
10g
$ 60.00

TCI Chemical
2-Nitrophenylacetic Acid >98.0%(GC)(T)
25g
$ 62.00

SynQuest Laboratories
2-Nitrophenylacetic acid
25 g
$ 20.00

SynQuest Laboratories
2-Nitrophenylacetic acid
100 g
$ 53.00

Sigma-Aldrich
2-Nitrophenylacetic acid 98%
25g
$ 68.80

Sigma-Aldrich
2-Nitrophenylacetic acid 98%
100g
$ 230.00

Frontier Specialty Chemicals
2-Nitrophenylacetic acid 99%
100g
$ 136.00

Frontier Specialty Chemicals
2-Nitrophenylacetic acid 99%
25g
$ 43.00

ChemScene
2-(2-Nitrophenyl)aceticacid 99.90%
500g
$ 99.00

Total 93 raw suppliers

Chemical Property of 2-Nitrophenylacetic acid

Chemical Property:

Appearance/Colour:yellow to beige crystalline powder
Vapor Pressure:2.4E-05mmHg at 25°C
Melting Point:137-140 °C(lit.)
Refractive Index:1.5468 (estimate)
Boiling Point:345.1 °C at 760 mmHg
PKA:4(at 25℃)
Flash Point:155.9 °C
PSA：83.12000
Density:1.407 g/cm³
LogP:1.74510
Storage Temp.:Store at RT.
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:181.03750770
Heavy Atom Count:13
Complexity:211

Purity/Quality:

99% ^*data from raw suppliers

2-Nitrophenylacetic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn, Xi
Hazard Codes:Xi,Xn
Statements: 36/37/38-68
Safety Statements: 26-36-37/39

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Nitrogen Compounds -> Nitros, Aromatic
Canonical SMILES:C1=CC=C(C(=C1)CC(=O)O)[N+](=O)[O-]
Uses 2-Nitrophenylacetic Acid is a useful research chemical. 2-Nitrophenylacetic acid was used as an internal standard in the determination of the theophylline solubilizer salicylamide-O-acetic acid.

Technology Process of 2-Nitrophenylacetic acid

There total 34 articles about 2-Nitrophenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.8%

: 88-72-2
1-methyl-2-nitrobenzene

: 95-92-1
oxalic acid diethyl ester

: 3740-52-1
2-(2-nitrophenyl)acetic acid

Guidance literature:: 1-methyl-2-nitrobenzene; oxalic acid diethyl ester; With sodium; In ethanol; at 20 - 45 ℃; for 3h;

With water; In ethanol; at 60 ℃; for 1h; Reagent/catalyst;

Reference yield: 90.0%

: 10565-14-7
Diethyl 2-(2-nitrophenyl)propanedioate

: 3740-52-1
2-(2-nitrophenyl)acetic acid

Guidance literature:: With hydrogenchloride; water; at 20 ℃; for 12h;
DOI:10.1071/CH13331

Reference yield: 87.0%

: 1141874-17-0
allyl 2-(2-nitrophenyl)acetate

: 3740-52-1
2-(2-nitrophenyl)acetic acid

Guidance literature:: allyl 2-(2-nitrophenyl)acetate; With sodium tetrahydroborate; In dimethyl sulfoxide; at 20 ℃;

With hydrogenchloride; water; In dimethyl sulfoxide; for 0.5h; chemoselective reaction;
DOI:10.1080/00397910902963694